Results 11 to 20 of about 137,019 (306)
Pure autonomic failure versus prodromal dysautonomia in Parkinson’s disease: Insights from the bedside [PDF]
Mov Disord Clin Pract, 2016 Autonomic failure may include orthostatic hypotension, supine hypertension, bowel and bladder disturbances, impaired thermal regulation, and sexual dysfunction, all of which can be features of Parkinson's disease (PD) and other a‐synucleinopathies.
Espay, Alberto J +6 more
core +4 more sources
Predicting phenoconversion in pure autonomic failure [PDF]
Neurology, 2020 To determine predicting factors and frequency of phenoconversion from pure autonomic failure (PAF) into a synucleinopathy with motor or cognitive involvement of multiple system atrophy (MSA), Parkinson disease (PD), or dementia with Lewy bodies (DLB).We performed a retrospective review of all patients with PAF from 2001 to 2011 evaluated at Mayo Clinic,
Phillip A. Low +6 more
europepmc +6 more sources
Renal Impairment of Pure Autonomic Failure [PDF]
Hypertension, 2009 Supine hypertension is difficult to manage in patients with pure autonomic failure (PAF), because treatment can worsen orthostatic hypotension. Supine hypertension in PAF has been associated with left ventricular hypertrophy, but end organ damage in the kidney has not been assessed.
David Robertson +7 more
europepmc +5 more sources
Pelvic autonomic dysfunction is common in patients with pure autonomic failure [PDF]
European Journal of NeurologyAbstractBackground and PurposePure autonomic failure (PAF) presents primarily as cardiovascular autonomic failure and may phenoconvert to other neurodegenerative disorders. However, the involvement of other autonomic functions has been poorly evaluated.
E. Vichayanrat +5 more
europepmc +4 more sources
Very late‐onset pure autonomic failure [PDF]
Movement Disorders, 2017 Nadia Stefanova +9 more
europepmc +4 more sources
Practical Neurology, 2017 Pure autonomic failure is a degenerative disorder of the peripheral autonomic nervous system. Patients experience symptomatic hypotension that requires them to sit, squat or lie down to prevent syncope. It is associated with characteristic histopathological findings, resulting in neuronal cytoplasmic inclusions in the peripheral autonomic nerves. These
Mariana D. Suarez +7 more
europepmc +7 more sources
Frequent Nocturnal Vocalization in Pure Autonomic Failure [PDF]
Journal of International Medical Research, 2008 Nocturnal vocalization is frequent in Parkinson's disease patients with rapid eye movement (REM) sleep behaviour disorder (RBD). We investigated the frequency of nocturnal vocalization and other sleep problems in patients with pure autonomic failure (PAF) and compared the results with idiopathic Parkinson's disease (IPD) and dementia with Lewy bodies (
K Kashihara, T Imamura, S Kawada, M Ohno
openaire +4 more sources
Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy [PDF]
Nature Communications, 2020 Autonomic dysfunction is a feature of some α-synucleinopathies, but there are no models of pure autonomic dysfunction associated with α-synuclein.
Xue-Jing Wang +10 more
doaj +2 more sources
Acta Médica Portuguesa, 1993 We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension.
J L Ducla-Soares +8 more
doaj +4 more sources
RBD in pure autonomic failure [PDF]
Journal of Clinical Images and Medical Case Reports, 2021 Pure autonomic failure is considered to be a degenerative condition of the autonomic nervous resulting from accumulation of alpha-synuclein in autonomic ganglia [1,2]. Lack of CNS involvement distinguishes this disorder from other synucleopathies with CNS involvement like MSA, DLB and PD. However, long term follow-up of PAF patients has shown that some
Shabeer Ahmad Paul +5 more
openaire +2 more sources