Results 261 to 270 of about 69,759 (309)

Cutaneous phosphorylated-synuclein: an early diagnostic biomarker for pure autonomic failure

Journal of Neurology Neurosurgery & Psychiatry
Background Pure autonomic failure (PAF) presents with progressive autonomic failure without other neurological features. Atypical presentations may lead to diagnostic uncertainty.
S. Koay, V. Provitera, G. Caporaso, E. Vichayanrat, F. Valerio, A. Stancanelli, I. Borreca, Michael P T Lunn, M. Nolano, V. Iodice   +9 more
semanticscholar   +1 more source

Autonomic hyperreflexia in pure progressive autonomic failure

Neurology, 1993
A 60-year-old woman suffered from recurrent episodes of fever, hypertension, facial flushing, vomiting, stridor, slowly progressive symptoms of hypohidrosis, and orthostatic hypotension. The episodes were synchronous with elevated catecholamine concentration in plasma and urine.
T, Mitsui, H, Kawai, E, Taguchi, H, Miyamoto, S, Saito   +4 more
openaire   +2 more sources

Pure Autonomic Failure

2018
Clinical case. Differential diagnosis: chronic variant of AAG, Synucleinopathies presenting with PAF phenotype. Diagnosis: Temporal profile of slowly progressive autonomic dysfunction without motor signs. Negative anti-ganglionic acetylcholine receptor antibodies (α3 nAChR).
Juan Idiaquez, Eduardo Benarroch, Martin Nogues   +2 more
openaire   +1 more source

Pure autonomic failure presenting as Harlequin syndrome

Autonomic Neuroscience, 2019
Pure autonomic failure (PAF) is a progressive syndrome of neurogenic orthostatic hypotension, widespread anhidrosis, urinary retention, and constipation without other neurologic manifestations. It is generally considered a peripheral ganglionic synucleinopathy. Natural history studies have described risk factors for the conversion of PAF to Parkinson's
James D, Triplett, Eduardo E, Benarroch, Jeremy K, Cutsforth-Gregory   +2 more
openaire   +2 more sources

[Pure autonomic failure].

Acta medica portuguesa, 1994
We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt.
J L, Ducla-Soares, A S, Guerreiro, P, Póvoa, E, Alvares, L, Guerreiro, F, Carrilho, M, Santos, J, Figueirinhas, M, Carvalho   +8 more
openaire   +1 more source

Pure autonomic failure with cold induced sweating

Autonomic Neuroscience, 2013
Pure autonomic failure (PAF) is a progressive autonomic neurodegenerative disorder. Cold induced sweating occurred in syndromes with mutations in CRLF1 and CLCF1 genes and in a case of cervical dissection. A patient with PAF developed sweating induced by cool ambient temperatures.
Idiaquez, Juan, Fadic, Ricardo, Verdugo, Renato, Idiaquez, Juan F., Iodice, Valeria, Low, David A., Mathias, C. J., Lombardi, Raffaela, G. LAURIA PINTER   +8 more
openaire   +3 more sources

Pure Progressive Autonomic Failure: A Clinicopathological Study

European Neurology, 1993
Two cases of pure progressive autonomic failure (PAF) are presented. A postmortem study of one case (case 2) showed a pathology resembling that of Parkinson's disease. Marked cell loss was noted in the substantia nigra, nucleus ceruleus, and intermediolateral column of the spinal cord, while cell loss in the sympathetic ganglion was not remarkable ...
Y, Terao, K, Takeda, M, Sakuta, T, Nemoto, T, Takemura, M, Kawai   +5 more
openaire   +2 more sources

Central dopamine deficiency in pure autonomic failure

Clinical Autonomic Research, 2008
Pure autonomic failure (PAF) and Parkinson's disease (PD) share several clinical laboratory abnormalities; however, PAF is not associated with parkinsonism. In this study, we tested the hypothesis that preservation of nigrostriatal dopaminergic innervation explains the absence of motor dysfunction in PAF.
David S, Goldstein, Courtney, Holmes, Takuya, Sato, Miya, Bernson, Neptune, Mizrahi, Richard, Imrich, Gilberto, Carmona, Yehonatan, Sharabi, Alexander O, Vortmeyer   +8 more
openaire   +2 more sources

Incidence of cerebrovascular lesions in pure autonomic failure

Autonomic Neuroscience, 2013
In pure autonomic failure (PAF) - a rare form of primary dysautonomia - some patients show cerebrovascular lesions usually found in hypertensive subjects. In an autonomic laboratory records of patients with a definitive diagnosis of PAF having had cerebral imaging (cMRI, cCT) were analysed retrospectively. Tilt table data (supine/tilted), 24 hour blood
Walter, Struhal, Heinz, Lahrmann, Christopher J, Mathias   +2 more
openaire   +2 more sources

Accumulation of alpha-synuclein in autonomic nerves in pure autonomic failure

Neurology, 2001
Pure autonomic failure is a progressive, adult-onset, degenerative disorder of the autonomic nervous system characterized clinically by orthostatic hypotension, and bladder and sexual dysfunction with no other associated neurologic deficits1. Pure autonomic failure is one of three disorders classified as primary autonomic failure, the other two being ...
H, Kaufmann, K, Hague, D, Perl
openaire   +2 more sources