Results 61 to 70 of about 9,473,382 (158)
Pure Red Cell Aplasia in a Cat
A 9-year-old male castrated American domestic shorthair cat was evaluated for lethargy, pallor, and anemia. A severe normocytic, normochromic, non-regenerative anemia with a mild leukocytosis and normal platelet count was identified. Testing was negative
Haber, Jennifer
core +4 more sources
Recurrent Severe Anaemia: A Rare Presentation of Parvovirus B19 Infection [PDF]
Secondary pure red cell aplasia is usually seen in immunocompromised hosts or patients who have chronic haemolytic anaemia, which is caused by blood transfusion related transmission.
Santokh Singh +4 more
doaj +1 more source
PARVOVIRUS B19-INDUCED PERSISTENT PURE RED CELL APLASIA IN A CHILD WITH T-CELL IMMUNODEFICIENCY
Persistent pure red cell aplasia can be a manifestation of parvovirus B19 infection in immunocompromised hosts. Failure of the humoral immune response to clear parvovirus B19 in such patients results in persistent pure red cell aplasia.
Turul, Tuba +5 more
core +1 more source
Isoniazid-induced pure red cell aplasia in two siblings
Pure red cell aplasia (PRCA) is a rare complication of treatment with isoniazid mainly observed in adults. We report two siblings who had anemia caused by PRCA during administration of isoniazid.
MARSEGLIA, GIAN LUIGI +3 more
core +2 more sources
Pure red-cell aplasia (PRCA) or erythroblastopenia is a rare type of anemia or disorder that can be either idiopathic or associated with certain autoimmune diseases and affect red blood cell (RBC) precursors1,2. The disease is often present at birth, and
Faheem Ahmed Memon
doaj
Abstract Background ABO‐incompatible (ABOi) hematopoietic stem cell transplantation (HSCT) is often associated with ABO discrepancies post‐HSCT. Re‐emergence of the patient's original type post‐HSCT may signal graft loss, disease relapse, recent transfusion, or soluble ABO antigen.
Sheri Hugan, Nada Naiyer, Laura Cooling
wiley +1 more source
RIFAMPICIN INDUCED PURE RED CELL APLASIA
BACKGROUND Pure red cell aplasia (PRCA) is a rare condition of severe anemia characterized by anabsence of erythroid precursor in the bone marrow, severe reticulocytopenia and normalplatelet and leukocyte count.
Marija Čeh
doaj
Abstract Background and Objectives Daratumumab, a therapeutic human anti‐CD38 monoclonal antibody, improves multiple myeloma outcomes but interferes with pre‐transfusion testing by binding CD38 on reagent red blood cells (RBCs), potentially masking clinically significant alloantibodies.
Arnaud Reggiani +30 more
wiley +1 more source
Background Pure red cell aplasia and moderate aplastic anemia are marrow failure states with an immune pathogenesis. Previously, we described short-term improvements in blood counts in two pilot studies treating moderate aplastic anemia (mAA) and pure ...
Elaine M. Sloand +6 more
doaj +1 more source
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source

