Results 51 to 60 of about 445,186 (328)

HEARING STATUS OF CHILDREN WITH BEHÇET’S DISEASE: A PROSPECTIVE PRELIMINARY STUDY

İstanbul Tıp Fakültesi Dergisi, 2021
Objective: We aimed to evaluate the hearing status of children with Behçet’s Disease (BD). Materials and Method: It is a prospective, cross-sectional, controlled study.
Nuray Aktay Ayaz, Gonca Keskindemirci, Zehra Çınar, Özgür Yiğit, Çiğdem Kalaycık Ertuğay, Mustafa Çakan, Şerife Gül Karadağ, Esat Alkaya   +7 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

The Correlation of Results between Pure Tone Audiometry and the Virtual Audiometer: A Simulated Air-Conduction Clinic-based Audiometer

Philippine Journal of Otolaryngology Head and Neck Surgery, 2008
The virtual audiometer (VA) is a software application that simulates a pure tone audiometer by delivering tones of different frequencies and intensities by air conduction.   Objective: To determine correlation between hearing thresholds measured by
Anne Elizabeth M. Javellana, Ray U. Casile   +1 more
doaj   +1 more source

A Pseudo-Haptic Method Using Auditory Feedback: The Role of Delay, Frequency, and Loudness of Auditory Feedback in Response to a User’s Button Click in Causing a Sensation of Heaviness

IEEE Access, 2022
One of the important challenges in the field of haptic engineering is the development of methods to present haptic information on commonly-used information devices equipped only with screens and speakers.
Seitaro Kaneko, Takumi Yokosaka, Hiroyuki Kajimoto, Takahiro Kawabe   +3 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Sequential Organization of Critical Periods in the Mouse Auditory System

Cell Reports, 2020
Summary: Critical periods—time windows of heightened plasticity in postnatal development—are specific to sensory features and are asynchronous. Whether they are timed by a temporally precise developmental program or are sequentially organized is not ...
Mari Nakamura, Patricia Valerio, Stitipragyan Bhumika, Tania Rinaldi Barkat   +3 more
doaj  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Association between a High-Potassium Diet and Hearing Thresholds in the Korean Adult Population

Scientific Reports, 2019
The aim of this study was to determine and evaluate the association between potassium intake and hearing thresholds in the Korean adult population. Data from the Korean National Health and Nutrition Examination Survey were analyzed.
Da Jung Jung, Jae Young Lee, Kyu Hyang Cho, Kyu-Yup Lee, Jun Young Do, Seok Hui Kang   +5 more
doaj   +1 more source