Results 71 to 80 of about 445,186 (328)

A web-based audiometry database system

open access: yesJournal of the Formosan Medical Association, 2014
To establish a real-time, web-based, customized audiometry database system, we worked in cooperation with the departments of medical records, information technology, and otorhinolaryngology at our hospital.
Chung-Hui Yeh   +5 more
doaj   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

open access: yesFEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti   +5 more
wiley   +1 more source

Hearing loss among hypertensive patients

open access: yesThe Egyptian Journal of Otolaryngology, 2019
Background Hypertension is a leading cause of mortality and morbidity worldwide. Hypertensives have been observed to have elevated hearing thresholds in various studies.
Stephen S. Yikawe   +6 more
doaj   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

The Binaural Localization of Pure Tones [PDF]

open access: yesThe Journal of the Acoustical Society of America, 1930
Measurements of phase difference and amplitude ratio of the sound entering the ears of a man-shaped wax dummy were taken with the source at varying azimuths around the head; at 256, 1024 and 1944 cycles per second; and at distances of 20, 50, 100 and 400 cm. from the head.
F. A. Firestone, E. R. Wightman
openaire   +2 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Identifying dead regions in the cochlea through the TEN Test [PDF]

open access: yes, 2006
SummaryAn audiogram is not sufficient to indicate cochlear dead regions.AimTo investigate cochlear dead regions in sensorineural hearing loss subjects using the TEN test.
Fernandes, João Cândido   +3 more
core   +4 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

The detection of markovian sequences of signals technical report no. 23 [PDF]

open access: yes
Detection of pure tone embedded in noise - Markov chains of ...
Carterette, E. C., Friedman, M. P.
core   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

open access: yesAdvanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso   +5 more
wiley   +1 more source

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