Results 81 to 90 of about 1,655,059 (390)
Functional magnetic resonance imaging measurements of sound-level encoding in the absence of background scanner noise [PDF]
, 2002 Effects of sound level on auditory cortical activation are seen in neuroimaging data. However, factors such as the cortical response to the intense ambient scanner noise and to the bandwidth of the acoustic stimuli will both confound precise ...
Akeroyd, MA +5 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Adult hearing screening: the Cyprus Pilot Program
Audiology Research, 2011 Hearing loss is the third most common condition affecting adults over 65 (Cruickshanks et al., 1998). It can affect quality of life, limiting the ability to communicate efficiently, and leading to isolation, psychological strain, and functional decline ...
C. Thodi +10 more
doaj +1 more source
Multilayer Spiking Neural Network for Audio Samples Classification Using SpiNNaker [PDF]
, 2016 Audio classification has always been an interesting subject of research inside the neuromorphic engineering field. Tools like Nengo or Brian, and hardware platforms like the SpiNNaker board are rapidly increasing in popularity in the neuromorphic ...
Cerezuela Escudero, Elena +6 more
core +1 more source
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
The detection of markovian sequences of signals technical report no. 23 [PDF]
Detection of pure tone embedded in noise - Markov chains of ...
Carterette, E. C., Friedman, M. P.
core +1 more source
Can unilateral, progressive or sudden hearing loss be immune-mediated in origin? [PDF]
, 2017 OBJECTIVE: The aim of the present study was to demonstrate that the positivity of nonspecific immunological tests could be found not only in bilateral hearing loss but also in unilateral cases, either sudden or progressive. METHOD: An observational case
Atturo, Francesca +4 more
core +1 more source
The Binaural Localization of Pure Tones [PDF]
The Journal of the Acoustical Society of America, 1930 Measurements of phase difference and amplitude ratio of the sound entering the ears of a man-shaped wax dummy were taken with the source at varying azimuths around the head; at 256, 1024 and 1944 cycles per second; and at distances of 20, 50, 100 and 400 cm. from the head.
F. A. Firestone, E. R. Wightman
openaire +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source