Results 271 to 280 of about 2,151,988 (346)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Comparative analysis of different biophysical techniques for exosome characterization. [PDF]

Sci Rep
Yu X, Wang Z, Zhang R, Guo W, Chang Q, Chu W, Zeng C, Wang L, Yu C, Li W.   +9 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Integrating Biological Architecture and Biomaterial Function: Exploring the Native Hydrogel Structure of Brown Seaweed. [PDF]

Macromol Biosci
Berglund L, Sharma R.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Clearance effects of blood purification on chlorfenapyr and tralopyril in chlorfenapyr poisoning patients. [PDF]

World J Emerg Med
Gong Y, Dong Y, An Y, Zhang H, Sun Y, Men Y, Gao H, Yao D, Meng N, Tian Y.   +9 more
europepmc   +1 more source

INVERTEBRATE UREASE: PURIFICATION AND CHARACTERIZATION OF UREASE FROM A LAND SNAIL

, 1970
John Alexander Mcdonald
openalex   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Recent Advances in Membrane Filtration and Purification Technologies. [PDF]

Membranes (Basel)
Khalil AM.
europepmc   +1 more source

Effects of Rna Purification Methods on Genome Editing in Olive Flounder and Turbot

Sishi Qin, Lijuan Wang, Zhihao Wu, Yaobo Jin, Yansong Liu, Feng You, Xungang Tan   +6 more
openalex   +1 more source