Results 151 to 160 of about 14,313 (250)

Immunization with purine salvation pathway recombinant enzymes induces the production of anti- Schistosoma mansoni immunoglobulines [PDF]

Schistosomiasis, a disease caused by the trematodes of the Schistosoma genus, affects about 240 million people worldwide. The Praziquantel (PZQ) is the drug used to treat this disease. However, reports of resistant strains reinforce the need to develop a
Adachi, Felipe de Pontes, Anibal, Fernanda de Freitas, Correia, Ricardo de Oliveira, Dejani, Naiara Naiana, Garratt, Richard Charles, Neris, Débora Meira, Oliveira, Sandra Regina Pereira de, Pereira, Humberto D'Muniz, Rodolpho, Joice Margareth de Almeida, Rodrigues, Vanderlei, Souza, Laís Cristina de   +10 more
core  

Adenosine deaminase from Plasmodium falciparum as a Potential Drug Target in Anti- Malarial Drug Designing: A Bioinformatic Approach [PDF]

, 2009
Parasites are responsible for a wide variety of infectious diseases causing an enormous health and economical blight. Malaria is one such prominent disease that causes widespread infections in humans and results in innumerable deaths annually.
Meenaa, V., Sasikumar, C., Srilakshmi, J. Kavitha, Sriram, S.   +3 more
core   +1 more source

Structure-Activity Relationships for a Collection of Structurally Diverse Inhibitors of Purine Nucleoside Phosphorylase.

, 2001
Adriano D. Andricopulo, Rosendo Augusto Yunes   +1 more
openalex   +2 more sources

Achieving the Ultimate Physiological Goal in Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase [PDF]

, 2003
Andrzej Lewandowicz, Peter C. Tyler, Gary B. Evans, Richard H. Furneaux, Vern L. Schramm   +4 more
openalex   +1 more source

Purine nucleoside phosphorylase deficiency induces p53-mediated intrinsic apoptosis in human induced pluripotent stem cell-derived neurons. [PDF]

Sci Rep, 2022
Tsui M, Biro J, Chan J, Min W, Dobbs K, Notarangelo LD, Grunebaum E.   +6 more
europepmc   +1 more source

Acid- and base-catalyzed ring-opening reactions or a sterically hindered epoxide [PDF]

, 1987
Bäuml, Englbert, Koschinsky, Rainer, Mayr, Herbert, Will, Elfriede   +3 more
core   +1 more source

A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori. [PDF]

Appl Microbiol Biotechnol, 2021
Wojtyś MI, Jaźwiec R, Kazazić S, Leščić Ašler I, Knežević P, Aleksić Sabo V, Luić M, Jagusztyn-Krynicka EK, Bzowska A.   +8 more
europepmc   +1 more source

Combined familial adenosine deaminase and purine nucleoside phosphorylase deficiencies. [PDF]

, 1988
A Shanon, Stanley Levin, Fanny Holtzman, F Brock-Sinai, A Abu-Said   +4 more
openalex   +1 more source

Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent. [PDF]

Sci Rep, 2021
Narczyk M, Mioduszewski Ł, Oksiejuk A, Winiewska-Szajewska M, Wielgus-Kutrowska B, Gojdź A, Cieśla J, Bzowska A.   +7 more
europepmc   +1 more source

Exploring Structure−Activity Relationships of Transition State Analogues of Human Purine Nucleoside Phosphorylase

, 2003
Gary B. Evans, Richard H. Furneaux, Andrzej Lewandowicz, Vern L. Schramm, Peter C. Tyler   +4 more
openalex   +1 more source