Results 151 to 160 of about 20,168 (266)

Adenosine deaminase from Plasmodium falciparum as a Potential Drug Target in Anti- Malarial Drug Designing: A Bioinformatic Approach [PDF]

, 2009
Parasites are responsible for a wide variety of infectious diseases causing an enormous health and economical blight. Malaria is one such prominent disease that causes widespread infections in humans and results in innumerable deaths annually.
Meenaa, V., Sasikumar, C., Srilakshmi, J. Kavitha, Sriram, S.   +3 more
core   +1 more source

Structure of E. coli 5′-methylthioadenosine/S-adenosylhomocysteine Nucleosidase Reveals Similarity to the Purine Nucleoside Phosphorylases [PDF]

, 2001
Jeffrey E. Lee, Ken Cornell, Michael K. Riscoe, P. Lynne Howell   +3 more
openalex   +1 more source

Purine Nucleoside Phosphorylase (PNP) as a Biomarker and Therapeutic Target in Muscle-Invasive Bladder Cancer

Clinical Medicine Insights: Oncology
Background: This study investigates the potential of purine nucleoside phosphorylase (PNP) as a biomarker and therapeutic target in muscle-invasive bladder cancer (MIBC).
Yanfei Chen, Peiyi Xian, Jianming Lu, Le Zhang, Chao Cai, Weide Zhong   +5 more
doaj   +1 more source

Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum

Proceedings of the National Academy of Sciences of the United States of America, 2018
R. G. Ducati, Hilda A. Namanja-Magliano, R. Harijan, J. E. Fajardo, A. Fiser, Johanna P. Daily, V. Schramm   +6 more
semanticscholar   +1 more source

Coordinate regulation of mRNAs encoding adenosine deaminase, purine nucleoside phosphorylase, and terminal deoxynucleotidyltransferase by phorbol esters in human thymocytes.

, 1988
Héctor Martínez-Valdez, Andrew Cohen
openalex   +1 more source

Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro [PDF]

, 2001
Tim U. Krohne, Srinivas Shankara, Michael Geißler, Bruce Roberts, Jack R. Wands, Hubert E. Blum, Leonhard Mohr   +6 more
openalex   +1 more source

Submolecular characterization of a mutant human purine-nucleoside phosphorylase.

, 1980
James A. McRoberts, David W. Martin
openalex   +1 more source

Purification and characterization of thermostable purine nucleoside phosphorylase of Bacillus stearothermophilus JTS 859.

, 1989
Nobuaki Hori, Mutsumi Watanabe, Yoshinari Yamazaki, Yoichi Mikami   +3 more
openalex   +2 more sources

1199. Novel Gene Therapy for Prostate Cancer: In Vivo-Targeted Expression of the E. Coli Purine Nucleoside Phosphorylase Gene by Adenoviral Delivery [PDF]

, 2002

openalex   +1 more source

PURINE NUCLEOSIDE PHOSPHORYLASES AS BIOCATALYSTS AND PHARMACOLOGICAL TARGETS

, 2017
A purine nucleoside phosphorylase from Aeromonas hydrophila (AhPNP) was successfully exploited to catalyze the ?one-pot, one-enzyme? regio- and stereoselective transfer of ?-D-ribose from a proper sugar donor (7-methylguanosine iodide) to a library of 6-substituted purine acceptors, resulting in the ?in batch?
openaire   +2 more sources