Synthesis of 6-Aryloxy- and 6-Arylalkoxy-2-chloropurines and Their Interactions with Purine Nucleoside Phosphorylase from Escherichia coli [PDF]
Agnieszka Bzowska+2 more
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D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint
Background Targeting glucose uptake by glucose transporter (GLUT) inhibitors is a therapeutic opportunity, but efforts on GLUT inhibitors have not been successful in the clinic and the underlying mechanism remains unclear.
Cheng-E Tu+9 more
doaj +1 more source
Immucillin‐H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange [PDF]
Fang Wang+5 more
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A resistant mutant of Plasmodium falciparum purine nucleoside phosphorylase uses wild-type neighbors to maintain parasite survival. [PDF]
Minnow YVT, Harijan RK, Schramm VL.
europepmc +1 more source
Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent. [PDF]
Narczyk M+7 more
europepmc +1 more source
Structure of E. coli 5′-methylthioadenosine/S-adenosylhomocysteine Nucleosidase Reveals Similarity to the Purine Nucleoside Phosphorylases [PDF]
Jeffrey E. Lee+3 more
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Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro [PDF]
Tim U. Krohne+6 more
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Submolecular characterization of a mutant human purine-nucleoside phosphorylase.
James A. McRoberts, David W. Martin
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