Purine nucleoside phosphorylase deficiency induces p53-mediated intrinsic apoptosis in human induced pluripotent stem cell-derived neurons. [PDF]
Tsui M+6 more
europepmc +1 more source
Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors [PDF]
openalex +1 more source
Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase [PDF]
Jason T. Maynes+6 more
openalex +1 more source
A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori. [PDF]
Wojtyś MI+8 more
europepmc +1 more source
Synthesis of 6-Aryloxy- and 6-Arylalkoxy-2-chloropurines and Their Interactions with Purine Nucleoside Phosphorylase from Escherichia coli [PDF]
Agnieszka Bzowska+2 more
openalex +1 more source
D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint
Background Targeting glucose uptake by glucose transporter (GLUT) inhibitors is a therapeutic opportunity, but efforts on GLUT inhibitors have not been successful in the clinic and the underlying mechanism remains unclear.
Cheng-E Tu+9 more
doaj +1 more source
Isolation of Nucleoside Metabolizing Enzymes from Alaska Pea Seeds (Pisum sativum L. cultivar Alaska) [PDF]
The activities of number of metabolizing enzymes were determined from dry Alaska Pea Seeds (Pisum sativum L. cultivar Alaska). Then tested for presence of three groups of enzymes; nucleosidase, deaminases and phosphorylases. The highest activity of the
Altawil, Zahrah Mohammad
core +1 more source
Monomeric purine nucleoside phosphorylase from rabbit liver. Purification and characterization.
Arthur S. Lewis, Morton D. Glantz
openalex +1 more source
Immucillin‐H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange [PDF]
Fang Wang+5 more
openalex +1 more source