1199. Novel Gene Therapy for Prostate Cancer: In Vivo-Targeted Expression of the E. Coli Purine Nucleoside Phosphorylase Gene by Adenoviral Delivery [PDF]
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PURINE NUCLEOSIDE PHOSPHORYLASES AS BIOCATALYSTS AND PHARMACOLOGICAL TARGETS
A purine nucleoside phosphorylase from Aeromonas hydrophila (AhPNP) was successfully exploited to catalyze the ?one-pot, one-enzyme? regio- and stereoselective transfer of ?-D-ribose from a proper sugar donor (7-methylguanosine iodide) to a library of 6-substituted purine acceptors, resulting in the ?in batch?
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Suicide gene therapy-mediated purine nucleoside phosphorylase/fludarabine system for in vitro breast cancer model with emphasis on evaluation of vascular endothelial growth factor promoter efficacy. [PDF]
Abbaspour A, Esmaeilzadeh A, Sharafi A.
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Excellent In vivo Bystander Activity of Fludarabine Phosphate against Human Glioma Xenografts that Express the Escherichia coli Purine Nucleoside Phosphorylase Gene [PDF]
Jeong S. Hong+11 more
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Nicotinamide riboside-amino acid conjugates that are stable to purine nucleoside phosphorylase. [PDF]
Hayat F, Migaud ME.
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Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase via the Mannich Reaction. [PDF]
Gary B. Evans+3 more
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Purine Nucleoside Phosphorylase Deficiency: A Case Report of an Extremely Rare Disorder. [PDF]
Alasmari BG+4 more
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