Results 31 to 40 of about 148,305 (130)

Metabolism Meets Translation: Dietary and Metabolic Influences on tRNA Modifications and Codon Biased Translation

open access: yesWIREs RNA, Volume 16, Issue 2, March/April 2025.
Diet influences tRNA modifications and metabolism. Metabolic processes are essential for the synthesis of many tRNA modifications, which can impact metabolism by altering mRNA translation and bioenergetics pathways. We discuss the importance of studying tRNA modifications from the viewpoint of cellular metabolism to fully grasp the complexity of ...
Sherif Rashad, Aseel Marahleh
wiley   +1 more source

The Relationship between Moderate to Vigorous Physical Activity and Metabolic Syndrome: A Bayesian Measurement Error Approach [PDF]

open access: yesarXiv, 2023
Metabolic Syndrome (MetS) is a serious condition that can be an early warning sign of heart disease and Type 2 diabetes. MetS is characterized by having elevated levels of blood pressure, cholesterol, waist circumference, and fasting glucose. There are many articles in the literature exploring the relationship between physical activity and MetS, but ...
arxiv  

Determination of uric acid in serum using isotachophoresis [PDF]

open access: yes, 1980
An operational system is described for the isotachophoretic determination of uric acid in serum, making use of column coupling. The method has been compared with a standard enzymatic procedure. With the present technique small amounts of serum (ca. 3 μl)
Bruijn, de, C.H.M.M.   +4 more
core   +1 more source

Identification of CSPG4 as a Biomarker and Therapeutic Target for Infantile Post‐Hemorrhagic Hydrocephalus via Multi‐Omics Analysis

open access: yesAdvanced Science, Volume 12, Issue 6, February 10, 2025.
This study demonstrates that over‐representation of ferroptosis, calcium, calcium ion binding, and cell adhesion signaling pathways in cerebrospinal fluid is associated with infantile post‐hemorrhagic hydrocephalus (PHH). Importantly, the expression level of CSPG4 is correlated with PHH progression; and CSPG4 silencing suppresses the dysregulation of ...
Juncao Chen   +13 more
wiley   +1 more source

Inborn errors of metabolism (IEM): a general overview [PDF]

open access: yes, 2011
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of inborn errors of ...
Ritenuti, Michel
core  

Standard Protocols for Characterising Primary and In Vitro‐Generated Human Hepatocytes

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 3, February 2025.
ABSTRACT Hepatocyte‐like cells (HLCs) derived from pluripotent stem cells (PSCs) or direct reprogramming are an unlimited source of human hepatocytes for biomedical applications. HLCs are used to model human diseases, develop precise drugs and establish groundbreaking regenerative cell‐based therapies.
Zahra Heydari   +11 more
wiley   +1 more source

Clinical and Biochemical Footprints of Inherited Metabolic Diseases. XIV. Metabolic Kidney Diseases [PDF]

open access: yes, 2023
Kidney disease is a global health burden with high morbidity and mortality. Causes of kidney disease are numerous, extending from common disease groups like diabetes and arterial hypertension to rare conditions including inherited metabolic diseases ...
Blau, Nenad   +3 more
core   +1 more source

Antivirals in COVID‐19: A Focus on Pediatric Cardiac Patients

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
The COVID‐19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to prevent or manage the infection.
Dalia Safi   +4 more
wiley   +1 more source

Altered purine and pyrimidine metabolism in erythrocytes with purine nucleoside phosphorylase deficiency [PDF]

open access: yes, 1980
Purine and pyrimidine metabolism was compared in erythrocytes from three patients from two families with purine nucleoside phosphorylase deficiency and T-cell immunodeficiency, one heterozygote subject for this enzyme deficiency, one patient with a ...
A. Cohen   +49 more
core   +1 more source

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