Results 271 to 280 of about 25,184 (290)

[73] Chinese hamster purine nucleoside phosphorylase

1978
Publisher Summary This chapter describes the purification procedure of nucleoside phosphorylase enzyme from Chinese hamster V79 tissue culture cells. Purine nucleoside phosphorylase (purine nucleoside: orthophosphate ribosyltransferase) in eukaryotes catalyzes the reversible conversion among the purine bases, hypoxanthine and guanine, and their ...
openaire   +3 more sources

Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides

Biochemical Pharmacology, 1987
In an effort to develop more potent inhibitors of human purine nucleoside phosphorylase (PNP) as immunosuppressive and cancer chemotherapeutic agents, the affinity of the erythrocytic enzyme for 30 acyclic nucleosides, nucleotides and related compounds was determined.
Robert E. Parks, Karkas Jd, Li Sy, Johanna D. Stoeckler, Tolman Rl, Stein Jm, Chen A, Ashton Wt, Malcolm MacCoss   +8 more
openaire   +3 more sources

Purine nucleoside synthesis: an efficient method employing nucleoside phosphorylases

Biochemistry, 1981
An improved method for the enzymatic synthesis of purine nucleosides is described. Pyrimidine nucleosides were used as pentosyl donors and two phosphorylases were used as catalysts. One of the enzymes, either uridine phosphorylase (Urd Pase) or thymidine phosphorylase (dThd Pase), catalyzed the phosphorolysis of the pentosyl donor.
Joel Van Tuttle, Thomas A. Krenitsky, George W. Koszalka   +2 more
openaire   +3 more sources

Purine Nucleoside Phosphorylase of Bovine Liver Mitochondria

1991
Purine nucleoside phosphorylase (PNPase, purine nucleoside: orthophosphate ribosyltransferase E.C. 2.4.2.1) in mammals reversibly catalyzes the phosphorolysis of the purine ribonucleosides (deoxy)inosine and (deoxy)guanosine to (deoxy)ribose-l-phosphate and the respective base.
Roger A. Lewis, Robert K. Haag
openaire   +3 more sources

A Case with Purine Nucleoside Phosphorylase Deficiency Suffering from Late-Onset Systemic Lupus Erythematosus and Lymphoma

Journal of Clinical Immunology, 2020
B. Al-Saud, Zainab Al Alawi, Faisal Bin Hussain, M. Hershfield, F. Alkuraya, S. Al‐Mayouf   +5 more
semanticscholar   +1 more source

Purine Nucleoside Phosphorylase Inhibitor

Definitions, 2020

semanticscholar   +1 more source

Novel missense mutation in the purine nucleoside phosphorylase gene in a Japanese patient with purine nucleoside phosphorylase deficiency

Pediatrics International, 2002
Takeshi Sakiyama, Misao Owada, Masahiko Tsuda, Kenichi Horinouchi   +3 more
openaire   +3 more sources

Development of a new HPLC method using fluorescence detection without derivatization for determining purine nucleoside phosphorylase activity in human plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016
P. Giuliani, M. Zuccarini, S. Buccella, Margherita Rossini, I. D'alimonte, R. Ciccarelli, M. Marzo, A. Marzo, P. Di Iorio, F. Caciagli   +9 more
semanticscholar   +1 more source

Structural characterization of purine nucleoside phosphorylase from human pathogen Helicobacter pylori.

International Journal of Biological Macromolecules, 2017
Z. Štefanić, Goran Mikleušević, M. Luić, A. Bzowska, Ivana Leščić Ašler   +4 more
semanticscholar   +1 more source

Three-dimensional structure of E. Coli purine nucleoside phosphorylase at 0.99 Å resolution

, 2016
V. Timofeev, Yu. A. Abramchik, N. E. Zhukhlistova, T. Muravieva, R. Esipov, I. Kuranova   +5 more
semanticscholar   +1 more source