Results 311 to 320 of about 2,316,796 (350)
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Purinergic receptors in auditory neurotransmission
Hearing Research, 2003The effects of ATP (adenosine 5' triphosphate) analogs on gross cochlear potentials and single primary afferent discharge properties were studied by intracochlear perfusion in anesthetized guinea pigs. ATP-gamma-S was most potent, with betagammamethylene-ATP and Bz-ATP being significantly less effective.
Bardia Paki +3 more
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Purinergic receptors in gastrointestinal inflammation
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2008Purinergic receptors comprise a family of transmembrane receptors that are activated by extracellular nucleosides and nucleotides. The two major classes of purinergic receptors, P1 and P2, are expressed widely in the gastrointestinal tract as well as immune cells.
Rahul Bajaj +3 more
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PET Imaging of Purinergic Receptors
2020Over the recent years, interest in the purinergic signaling system has sparked in the field of positron emission tomography (PET). Purinergic receptors play key roles in physiological and pathological processes, although the exact role in these processes is not always fully understood.
Janssen, Bieneke +2 more
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Purinergic receptors in psychiatric disorders
Neuropharmacology, 2016Psychiatric disorders describe different mental or behavioral patterns, causing suffering or poor coping of ordinary life with manifold presentations. Multifactorial processes can contribute to their development and progression. Purinergic neurotransmission and neuromodulation in the brain have attracted increasing therapeutic interest in the field of ...
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The enteric purinergic P2Y1 receptor
Current Opinion in Pharmacology, 2006Significant recent discoveries have shown that the P2Y(1) purinergic receptor subtype is expressed in the enteric nervous system and at intestinal neuromuscular junctions. Secretomotor neurons, which release vasoactive intestinal peptide at their junctions with intestinal secretory glands, express the P2Y(1) receptor.
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Purinergic receptors in embryonic and adult neurogenesis
Neuropharmacology, 2016ATP (adenosine 5'-triphosphate), one of the most ancient neurotransmitters, exerts essential functions in the brain, including neurotransmission and modulation of synaptic activity. Moreover, this nucleotide has been attributed with trophic properties and experimental evidence points to the participation of ATP-activated P2X and P2Y purinergic ...
Ágatha Oliveira +2 more
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Purinergic receptors and metabolic function
Drug Development Research, 1996Blood glucose concentration is a signal for the endocrine pancreas to release insulin or glucagon. Insulin lowers the level of glucose by inhibiting the hepatic glucose production and stimulating glucose utilization by skeletal muscles and adipocytes.
P. Petit +3 more
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Purinergic Receptors and Hepatobiliary Function
2003Publisher Summary This chapter describes the basic mechanisms that contribute to purinergic signaling in liver cells by focusing on a molecular and pharmacologic description of the receptors present, the mechanisms and regulation of adenosine triphosphate (ATP) release, and nucleotide/nucleoside degradation and reuptake pathways.
Andrew P. Feranchak, J. Gregory Fitz
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Is the benzodiazepine receptor purinergic?
European Journal of Pharmacology, 1979H.W. Damm +2 more
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