Results 131 to 140 of about 10,536 (182)
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Idiopathic Thrombocytopenic Purpura
Primary Care: Clinics in Office Practice, 1980The finding of thrombocytopenia with normal or increased megakaryocytes on bone marrow aspirate supports the diagnosis of ITP. It is essential, however, that every effort be made to exclude other causes of the consumption of platelets. Most cases of chronic ITP are immune in origin; consequently, steroid therapy is the initial treatment of choice ...
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Idiopathic Thrombocytopenic Purpura
Archives of Internal Medicine, 1986To the Editor. —There is more evidence that genetic factors predispose to chronic immunologic thrombocytopenic purpura (ITP) than is summarized by Bogart and Wittels in their article on ITP in two elderly siblings in the December 1985 issue of theArchives.
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Idiopathic Autoimmune Thrombocytopenic Purpura
Advances in Pediatrics, 1994Childhood ITP occurs in acute and chronic forms. In general, both diseases are mild and can be managed conservatively. Approaches to therapy are highly controversial and vary widely among pediatricians and academic centers. Approximately 5% of children with ITP will develop chronic disease with severe thrombocytopenia and bleeding.
J, Kurtzberg, J A, Stockman
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Idiopathic thrombocytopenic purpura
Current Paediatrics, 1995Idiopathic thrombocytopenic purpura in children usually a self limiting disorder. It may follow a viral infection or immunisation and is caused by an inappropriate response of the immune system. About 20-30% of children will fail to remit over six months (chronic idiopathic thrombocytopenic purpura).
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Idiopathic Thrombocytopenic Purpura
New England Journal of Medicine, 1966A CHANGE in the concepts regarding idiopathic thrombocytopenic purpura has occurred during the past fifteen years mainly because of the recognition of three important facts: The thrombocytopenia is the result of increased platelet destruction. The old hypothesis, originally postulated by Frank,1 , 2 of a toxic depression of megakaryocytes and their ...
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Infantile Idiopathic Thrombocytopenic Purpura
Pediatric Hematology and Oncology, 1990Idiopathic thrombocytopenic purpura (ITP) in childhood is a benign disease, as only 10% to 20% of the patients have a chronic course. A retrospective study of 57 ITP patients ranging in age from four months to two years revealed that 30% of them proceeded to chronicity.
A, Ballin +8 more
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Idiopathic Thrombocytopenic Purpura in Children
Seminars in Thrombosis and Hemostasis, 2008ITP in childhood is most often of the acute, self-limited variety, with spontaneous recovery occurring within a matter of days or weeks. In many of these children, acute thrombopenic purpura follows in the wake of a viral infection. While the pathogenesis is not entirely clear, it seem probable that the platelet membrane is altered by virus or by ...
J M, Lusher, R, Iyer
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Idiopathic Thrombocytopenic Purpura in Pregnancy
Clinics in Perinatology, 1985Idiopathic thrombocytopenic purpura (ITP) frequently occurs in young women, and is therefore encountered in pregnancy. Any woman with a history of ITP, regardless of her clinical status, has some risk of delivering a thrombocytopenic infant, since the antiplatelet antibodies cross the placenta. Methods for predicting which infants are at high risk, for
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Idiopathic Thrombocytopenic Purpura in Adults
Journal of Pediatric Hematology/Oncology, 2003Immune thrombocytopenic purpura (ITP) is an organ-specific autoimmune disorder in which platelets opsonized by antiplatelet antibodies are destroyed by the reticuloendothelial system. As a result the peripheral blood platelet count is low; if sufficiently severe, it may lead to bruising and mucocutaneous bleeding.
Drew, Provan, Adrian, Newland
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Thrombokinetics in Idiopathic Thrombocytopenic Purpura*
British Journal of Haematology, 1970Summary Measurements of platelet production in 16 patients with idiopathic thrombocytopenic purpura (ITP) demonstrate that megakaryocytopoiesis (total thrombopoiesis) and platelet turnover (effective thrombopoiesis) are increased in parallel to as much as 8 times normal. The marrow megakaryocytes show changes characteristic of stimulated thrombopoiesis.
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