Results 171 to 180 of about 156,843 (219)

Idiopathic thrombocytopenic purpura and pregnancy

International Journal of Gynecology & Obstetrics, 1999
Ž . Idiopathic thrombocytopenic purpura ITP is a common disease of young women and its management during pregnancy is a clinical problem often w x faced by physicians 1 . Treatment is required for women with platelet counts -10=10rl and women with platelet counts 10]30=10rl who are in the second or third trimester or are bleedw x ing 2 .
D M, Paternoster, C, Santarossa, G, Manfreda   +2 more
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Idiopathic Thrombocytopenic Purpura

New England Journal of Medicine, 1966
A CHANGE in the concepts regarding idiopathic thrombocytopenic purpura has occurred during the past fifteen years mainly because of the recognition of three important facts: The thrombocytopenia is the result of increased platelet destruction. The old hypothesis, originally postulated by Frank,1 , 2 of a toxic depression of megakaryocytes and their ...
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Idiopathic Autoimmune Thrombocytopenic Purpura

Advances in Pediatrics, 1994
Childhood ITP occurs in acute and chronic forms. In general, both diseases are mild and can be managed conservatively. Approaches to therapy are highly controversial and vary widely among pediatricians and academic centers. Approximately 5% of children with ITP will develop chronic disease with severe thrombocytopenia and bleeding.
J, Kurtzberg, J A, Stockman
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TREATMENT OF IDIOPATHIC THROMBOCYTOPENIC PURPURA

Journal of the American Medical Association, 1959
The course of idiopathic thrombocytopenic purpura (ITP) was studied in four groups of patients. In the first group of 24 patients the therapy did not include either steroids or splenectomy, but 10 had complete remissions within a year after the ITP was recognized. All 10 were less than 10 years of age and each had had an infection within a month before
A F, CARPENTER, M M, WINTROBE, E A, FULLER, A, HAUT, G E, CARTWRIGHT   +4 more
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Idiopathic Thrombocytopenic Purpura in Adults

Southern Medical Journal, 1988
Idiopathic thrombocytopenic purpura (ITP) is a primary immune thrombocytopenia that is typically manifested in adults by acute bleeding, severe thrombocytopenia, and normal to increased megakaryocytes in the bone marrow. Labeling studies suggest that most patients with ITP have an IgG antibody directed against the platelet membrane resulting in ...
D P, Brannan, T H, Guthrie
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Thrombokinetics in Idiopathic Thrombocytopenic Purpura*

British Journal of Haematology, 1970
Summary Measurements of platelet production in 16 patients with idiopathic thrombocytopenic purpura (ITP) demonstrate that megakaryocytopoiesis (total thrombopoiesis) and platelet turnover (effective thrombopoiesis) are increased in parallel to as much as 8 times normal. The marrow megakaryocytes show changes characteristic of stimulated thrombopoiesis.
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Treatment of Idiopathic Thrombocytopenic Purpura

Hospital Practice, 1983
ITP is a common disease that is sorely in need of better management. Treatment strategy requires consideration of both long-term benefits and long-term hazards of each available therapeutic option. This discussion reviews conventional therapy as well as newer approaches to refractory ITP, including immunosuppressants, vinca alkaloids, colchicine ...
W J, Harrington, Y S, Ahn, J J, Byrnes, A G, So, R, Mylvaganam, L M, Pall   +5 more
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Management of idiopathic thrombocytopenic purpura

The Indian Journal of Pediatrics, 1998
Idiopathic thrombocytopenic purpura is not an uncommon bleeding disorder with a prevalence of 40-80 per million children per year. Over the last six decades, the subject of ITP has attracted the attention of pediatricians and hematologists. It is one of the subjects which has many controversies because of its unpredictable course heralded by remission ...
V P, Choudhry, R, Kashyap, H P, Pati
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Splenectomy for Idiopathic Thrombocytopenic Purpura

Archives of Surgery, 1966
IDIOPATHIC thrombocytopenic purpura (ITP) is a disease entity characterized by a decrease in the circulating platelets despite an increase in megakaryocytes seen in the marrow. There is a concomitant bleeding tendency, but the precise pathophysiological cause or etiology is unknown.
G E, Block, R, Evans, R, Zajtchuk
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Idiopathic Thrombocytopenic Purpura in Pregnancy

Clinics in Perinatology, 1985
Idiopathic thrombocytopenic purpura (ITP) frequently occurs in young women, and is therefore encountered in pregnancy. Any woman with a history of ITP, regardless of her clinical status, has some risk of delivering a thrombocytopenic infant, since the antiplatelet antibodies cross the placenta. Methods for predicting which infants are at high risk, for
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