Idiopathic thrombocytopenic purpura
Idiopathic thrombocytopenic purpura (ITP) is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause.
L Kayal, S Jayachandran, Khushboo Singh
doaj +4 more sources
Canine Idiopathic Thrombocytopenic Purpura [PDF]
Canine idiopathic thrombocytopenic purpura (ITP) is a disease in which antibodies bound to the surface of platelets mediate premature platelet destruction by macrophages. ITP in dogs and chronic ITP in humans are analogous diseases. This article draws on information from the literature on ITP in dogs and in humans, and reviews the pathogenesis ...
D C, Lewis, K M, Meyers
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Vonoprazan‐Containing Triple Therapy Based on Clarithromycin Susceptibility May Be Definitive Treatment Strategy for Eradication of Helicobacter pylori [PDF]
ABSTRACT Aims Helicobacter pylori (H.pylori) eradication therapy often fails to eradicate clarithromycin (CAM)‐resistant strains. Individualized therapy with proton pump inhibitors and metronidazole instead of CAM could be effective for first‐line eradication based on CAM sensitivity tests. However, on the basis of these tests, whether vonoprazan (VPZ)
Murata M +14 more
europepmc +2 more sources
Pathogenicity of anti-ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. [PDF]
BACKGROUND: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency.
Crawley, JT +3 more
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Idiopathic Thrombocytopenic Purpura after Mastectomy and Axillary Lymph Node Dissection
First described in 1916, idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease resulting in the destruction of platelets. Here, we present a case of an 85-year-old patient diagnosed with invasive ductal carcinoma of the breast whose surgical
Wil L. Santivasi +2 more
doaj +1 more source
Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine +11 more
core +1 more source
Purpura with regular shape in an adolescent: Beware of dermatitis artefacta
BackgroundPurpura is common in pediatric patients, mostly diagnosed as IgA-related vasculitis (Henoch–Schönlein purpura), idiopathic thrombocytopenic purpura (ITP), and thrombotic thrombocytopenic purpura (TTP). However, in some cases, for example, cases
Yuhao Chen +4 more
doaj +1 more source
Pseudotumor Cerebri and Hemolytic Uremic Syndrome, A Rare Association. [PDF]
ABSTRACT Hemolytic uremic syndrome can present with central nervous system involvement. Idiopathic intracranial hypertension (IIH) is among the possible neurological manifestations of HUS, and clinicians should remain vigilant for extrarenal complications while treating patients with HUS.
Ali A +6 more
europepmc +2 more sources
Manajemen Anestesi pada Seksio Sesarea dengan Idiopathic Thrombocytopenic Purpura: Serial kasus
Trombositopenia merupakan perubahan hemostasis yang umum terjadi pada wanita hamil, namun jarang ditemukan kondisi berat. Idiopathic thrombocytopenic purpura (ITP) merupakan salah satu penyebab trombositopenia pada wanita hamil.
Achmad Haryanto +2 more
doaj +1 more source
Adult Idiopathic Thrombocytopenic Purpura
Idiopathic thrombocytopenic purpura (ITP) in adults is an autoimmune disorder characterised by persistent thrombocytopenia due to autoantibodies directed against platelet antigens. There have been major advances in our understanding of the pathophysiology of ITP and an increasing number of diagnostic tests and treatments available.
Mead, A, Newland, A, Provan, D
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