Results 21 to 30 of about 17,830 (205)
Immune Thrombocytopenia as a Consequence of Rocky Mountain Spotted Fever
Primary immune thrombocytopenia (ITP) – also called idiopathic thrombocytopenic purpura or immune thrombocytopenic purpura – is an acquired thrombocytopenia caused by autoantibodies against platelet antigens.
Cherisse Baldeo+2 more
doaj +1 more source
Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine+11 more
core +1 more source
Adult Idiopathic Thrombocytopenic Purpura
Idiopathic thrombocytopenic purpura (ITP) in adults is an autoimmune disorder characterised by persistent thrombocytopenia due to autoantibodies directed against platelet antigens. There have been major advances in our understanding of the pathophysiology of ITP and an increasing number of diagnostic tests and treatments available.
Mead, A, Newland, A, Provan, D
openaire +3 more sources
Influences of various hormones on the megakaryocyte in bone-marrow tissue culture [PDF]
In our study on the influences of various hormones and various endocrines on the megakaryocyte function by means of bone-marrow tissue culture, we obtained the following. 1.
Hiraki, Kiyoshi+2 more
core +1 more source
Idiopathic Thrombocytopenic Purpura (ITP) [PDF]
Sir.—I read with interest the article by Movassaghi et al entitled "Antiplatelet Antibodies in Childhood Idiopathic Thrombocytopenic Purpura" (Journal133:257-259, 1979). However, I cannot agree with their conclusion that platelet antibody usually disappears with recovery from thrombocytopenia in childhood ITP. We have already shown in three chronic and
openaire +4 more sources
Helicobacter pylori Eradication in Patients with Immune Thrombocytopenic Purpura: A Review and the Role of Biogeography [PDF]
Idiopathic thrombocytopenic purpura (ITP) is typically a diagnosis of exclusion, assigned by clinicians after ruling out other identifiable etiologies. Since a report by Gasbarrini et al.
Beck, Paul L.+3 more
core +1 more source
Idiopathic thrombocytopenic purpura
Point(1)診断は血小板減少をきたす他の疾患の除外を基本とする.(2)血小板数と出血症状の程度,背景因子やライフスタイルに基づいて治療適応を決める.(3)治療はまずステロイド療法,次いで摘脾を行う.(4)ITPと診断されればまずH. pyloriを検索し,陽性であれば除菌療法を優先する.
openaire +3 more sources
Background Type G immunoglobulins against ADAMTS13 are the primary cause of acquired (idiopathic) thrombotic thrombocytopenic purpura. However, the domains of ADAMTS13 which the type G anti-ADAMT13 immunoglobulins target have not been investigated in a ...
X. Long Zheng+7 more
doaj +1 more source
Idiopathic thrombocytopenic purpura: current concepts in pathophysiology and management. [PDF]
Idiopathic thrombocytopenic purpura (ITP) is characterized by a low platelet count, which is the result of both increased pla- telet destruction and insufficient platelet production.
Amadori, S+5 more
core +1 more source
Abstract Background Cardiac surgery on cardiopulmonary bypass (CPB) may alter platelet (PLT) function causing bleeding. The goal of this study is to evaluate the hemostatic effect of PRT‐PLTs compared to untreated PLTs stored in platelet additive solution (PAS) following transfusion in bleeding patients undergoing cardiac surgery on CPB.
Magali J. Fontaine+11 more
wiley +1 more source