IDIOPATHIC THROMBOCYTOPENIC PURPURA (i.T.P.) [PDF]
The course of t he disorder is acute and chronic.The acute form o f the disease occurs most c ommonly in children , but is seen i n adults as well . The chronic recurrent f orm occurs most o f t e n in women between t wenty and forty years of age.
Sh. MOHAMEDI M ZAMANIANPOUR ML GHASEMI
doaj +1 more source
Bone marrow examination findings at aga Khan University Hospital, Nairobi [PDF]
Objective: To establish the bone marrow examination findings and determine the indication for bone marrow examination. Design: A retrospective audit. Setting: Aga Khan University Hospital, Nairobi.
Malkit, Riyat, Okinda, Nancy
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A Difficult‐to‐Manage Case of Primary Idiopathic Erythromelalgia—Case Report
ABSTRACT Erythromelalgia is a rare condition with symptoms of erythema, warmth, and painful extremities exacerbated by warmth and relieved by cooling. Pain management is often challenging. The sodium channel blocker, lacosamide, was most effective in this patient.
Sarah Wide +3 more
wiley +1 more source
Refractory Immune Thrombocytopenia Successfully Treated with High-Dose Vitamin D Supplementation and Hydroxychloroquine: Two Case Reports [PDF]
Introduction: Immune thrombocytopenic purpura is thought to be characterized by an immune response against the host’s own platelets. If the thrombocytopenia is severe, patients are initially treated with high-dose steroids.
Bockow, Barry, Bockow, Tamara B
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Successful Treatment of Aplastic Anemia With Eltrombopag During Pregnancy: A Short Report
ABSTRACT Introduction Aplastic anemia (AA) is a rare bone marrow failure syndrome with pancytopenia, mainly due to immune‐mediated stem cell destruction. First‐line therapy for acquired severe AA ≥ 50 years/non‐severe AA (NSAA) requiring treatment is immunosuppressive therapy with horse anti‐thymocyte globulin, cyclosporine A (CSA), and eltrombopag ...
Sandra M. Frey +3 more
wiley +1 more source
Our case highlights the possible coexistence of essential thrombocythemia (ET) and idiopathic thrombocytopenic purpura (ITP), two pathological entities with opposite clinical and laboratory manifestations.
Antonio Carruale +5 more
doaj +1 more source
Trombocitopenia inmune primaria en pacientes de edad avanzada : experiencia en un centro [PDF]
Estudi descriptiu dels pacients majors de 60 anys amb diagnòstic de trombocitopènia immune primària en un centre. S'han revisat característiques bàsiques en el moment de l'inici de la malaltia, així com les diferents línies de tractament, resposta ...
López Pavía, María de la Encarnación +2 more
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Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. [PDF]
Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder which presents with isolated thrombocytopenia and risk of hemorrhage. While most children with ITP promptly recover with or without drug therapy, ITP is persistent or chronic in ...
Bennett, Carolyn M. +23 more
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A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
Eltrombopag: an update on the novel, non-peptide thrombopoietin receptor agonist for the treatment of immune thrombocytopenia [PDF]
Immune thrombocytopenia (ITP) is characterised by a transient or persistent decrease in platelets accompanied by an increased risk of bleeding, which can have a significant negative impact on patients' health-related quality of life.
Imbach, Paul, Kühne, Thomas
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