Results 71 to 80 of about 10,614 (201)

Single‐Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF Secretion

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang   +5 more
wiley   +1 more source

Association between oral fluoroquinolones and seizures: A self-controlled case series study.

open access: yes, 2016
OBJECTIVES: The aim of this study was to investigate the association and to estimate the crude absolute risk of seizure among patients exposed to fluoroquinolones (FQs) in Hong Kong and the United Kingdom. METHODS: A self-controlled case series study was
Chan, Esther W   +5 more
core   +2 more sources

Concept and application of a computational vaccinology workflow [PDF]

open access: yes, 2010
BACKGROUND : The last years have seen a renaissance of the vaccine area, driven by clinical needs in infectious diseases but also chronic diseases such as cancer and autoimmune disorders.
Fechete, Raul   +6 more
core   +2 more sources

Adult‐Onset Still's Disease Complicated by Secondary Hemophagocytic Lymphohistiocytosis: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Adult‐onset Still's disease (AOSD) is a rare autoinflammatory disorder characterized by fever, rash, joint pain, and elevated ferritin levels. Systemic inflammation can trigger an exaggerated immune response, leading to secondary hemophagocytic lymphohistiocytosis (HLH).
Vasileios Patriarcheas   +8 more
wiley   +1 more source

Open heart surgery for cyanotic heart disease in a child with immune thrombocytopenic purpura:a case report

open access: yesIndian Journal of Anaesthesia, 2007
Acute immune thrombocytopenic purpura in children, though a benign self limiting condition, at times complicated with life threatening haemorrhage. In spite of bleeding episode it is inevitable that surgical procedure will be performed on patients with ...
Minati Choudhury, Nirvik Pal, Usha Kiran
doaj  

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

Severe thrombocytopenia in patients with idiopathic pulmonary arterial hypertension provided several strategies for lung transplantation

open access: yesPulmonary Circulation, 2020
While the prognosis of idiopathic pulmonary arterial hypertension has improved significantly due to newer medications, lung transplantation remains a critical therapeutic option for severe pulmonary arterial hypertension.
Takayuki Kobayashi   +8 more
doaj   +1 more source

Dictamen Preliminar de Evaluación de Tecnología Sanitaria N° 010-SDEPFYOTS-DETS-IETSI-2016. Seguridad y eficacia del uso de el trombopag en púrpura trombocitopénica inmune primaria que ha fracasado a la primera línea de tratamiento [PDF]

open access: yes, 2016
En este documento se plasma la evaluación de la eficacia y seguridad del uso del producto farmacéutico eltrombopag en el tratamiento de púrpura trombocitopénica inmune primaria que ha fracasado a la primera línea de tratamiento; cuyos resultados ...
Castro Reyes, Maribel Marilú   +5 more
core  

Tronbozitopenia immune primarioa: Basurtu Unibertsitate Ospitalean emandako azken 8 urteetako kasuen errebisioa [PDF]

open access: yes, 2019
[EUS] Tronbozitopenia Immune Primarioa (PTI) umeetan eman daitekeen gaixotasun hematologiko autoimmunea da. Definizioz, PTI kontsideratzeko, odol periferikoko plaketa zenbaketan 100.000/mmc-tik beherako jaitsiera isolatua eman ...
Goikoetxea Burguillo, Jon
core   +3 more sources

Recurrent Acute Myocardial Infarction in Patients with Immune Thrombocytopenic Purpura

open access: yesJournal of Patient-Centered Research and Reviews, 2014
Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura, is an acquired immune-mediated disease of adults and children characterized by a transient or persistent decrease of platelets and, depending upon the degree of ...
Fengyi Shen, Tonga Nfor, Tanvir Bajwa
doaj   +1 more source

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