Results 91 to 100 of about 130,655 (306)

A Rare Immune Thrombocytopenia Caused by Brucellosis: A Case Report [PDF]

Rwanda Medical Journal, 2021
Immune thrombocytopenia is an autoimmune disorder characterized by accelerated platelet destruction. It is occasionally associated with accompanying infections. Here we report a case of acute brucellosis that presented with immune thrombocytopenia.
O. Kurtkulagi, G. Aktas, S. Bilgin, T. Taslamacioglu Duman, B. M. Atak Tel   +4 more
doaj  

Metric-space analysis of spike trains: theory, algorithms, and application [PDF]

Network 8, 127-164 (1997), 1998
We present the mathematical basis of a new approach to the analysis of temporal coding. The foundation of the approach is the construction of several families of novel distances (metrics) between neuronal impulse trains. In contrast to most previous approaches to the analysis of temporal coding, the present approach does not attempt to embed impulse ...
arxiv  

Pediatric thrombotic thrombocytopenic purpura

European Journal of Haematology, 2018
Child‐onset thrombotic thrombocytopenic purpura (TTP) is a rare entity of thrombotic microangiopathy (TMA). The pathophysiology of the disease is based on a severe functional deficiency of ADAMTS13 (activity
B. Joly, P. Coppo, A. Veyradier
semanticscholar   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia–Parkinsonism

Neurobiology of Disease, 2015
Loss-of-function mutations in the α3 isoform of the sodium pump are responsible for Rapid Onset Dystonia–Parkinsonism (RDP). A pharmacologic model of RDP replicates the most salient features of RDP, and implicates both the cerebellum and basal ganglia in
Rachel Fremont, Ambika Tewari, Kamran Khodakhah   +2 more
doaj  

Bad-Looking, Good-Natured Disease: Acute Hemorrhagic Edema of Infancy

Güncel Pediatri, 2017
Acute hemorrhagic edema of infancy is a skin limited leukocytoclastic vasculitis occurring in children younger than 2 years old. Although it has an alarming start, it has a good prognosis.
Esra Ülgen Temel, Nefise Arıbaş Öz, Ramazan Cahit Temizkan, Burcu Hıdımoğlu, Kenan Kocabay   +4 more
doaj   +1 more source

Risk Factors Associated with Renal Involvement in Childhood Henoch-Schönlein Purpura: A Meta-Analysis

PLoS ONE, 2016
Background and objective Henoch-Schönlein purpura (HSP) is an important cause of chronic kidney disease in children. This meta-analysis identified risk factors associated with renal involvement in childhood HSP. Methods PubMed, Embase, and Web of Science
Han Chan, Yangzhang Tang, Xiaoyan Lv, Gaofeng Zhang, Mo Wang, Haiping Yang, Qiu Li   +6 more
semanticscholar   +1 more source

Obstetric and Gynaecological Challenges and Outcomes in Women and Girls With Glanzmann's Thrombasthenia

Haemophilia, EarlyView.
ABSTRACT Introduction Glanzmann's thrombasthenia (GT) is an inherited platelet function disorder that may manifest with significant bleeding symptoms; in women and girls (W&Gs), heavy menstrual bleeding (HMB) is very common. GT in pregnancy is associated with an increased risk of postpartum haemorrhage (PPH).
Deborah Obeng‐Tuudah, Ahmad Tarawah, Melike Ozkan, Rezan Abdul‐Kadir   +3 more
wiley   +1 more source

Which spike train distance is most suitable for distinguishing rate and temporal coding? [PDF]

arXiv, 2017
Background: It is commonly assumed in neuronal coding that repeated presentations of a stimulus to a coding neuron elicit similar responses. One common way to assess similarity are spike train distances. These can be divided into spike-resolved, such as the Victor-Purpura and the van Rossum distance, and time-resolved, e.g. the ISI-, the SPIKE- and the
arxiv  

Caplacizumab reduces the frequency of major thromboembolic events, exacerbations and death in patients with acquired thrombotic thrombocytopenic purpura

Journal of Thrombosis and Haemostasis, 2017
Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic (TE) events, exacerbations and death was studied. Fewer caplacizumab‐treated patients had a major
F. Peyvandi, M. Scully, J. A. Hovinga, P. Knöbl, S. Cataland, K. D. Beuf, F. Callewaert, H. Winter, R. Zeldin   +8 more
semanticscholar   +1 more source