Results 121 to 130 of about 150,260 (318)

Interventional varicose vein therapy using endoluminal laser ablation (1940 nm) in patients with Ehlers‐Danlos syndromes: two case reports

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary In patients with Ehlers‐Danlos syndrome, the presence of chronic venous insufficiency poses a particular challenge for physicians when determining the indication for surgical treatment. Due to vascular fragility, complications such as vascular tears or ruptures with difficult hemostasis and potentially life‐threatening consequences occur ...
Dennis Braß   +2 more
wiley   +1 more source

An extreme type of new onset refractory status epilepticus with stimulus‐induced seizures in pharmacological isoelectric states

open access: yesEpilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is a common neurological emergency associated with high morbidity and mortality. SE is classified as refractory when it persists despite benzodiazepine and second‐line antiseizure medication. Managing refractory SE in the intensive care setting often requires high doses of sedative drugs, which can induce ...
Julie Lévi‐Strauss   +6 more
wiley   +1 more source

Rare onset of congenital thrombotic thrombocytopenic purpura during pregnancy: A novel ADAMTS13 gene variant. [PDF]

open access: yesTransfusion
Abstract Background Congenital thrombotic thrombocytopenic purpura (cTTP) is a rare autosomal recessive thrombotic microangiopathy caused by biallelic mutations in ADAMTS13, leading to severe enzyme deficiency. The absence of ADAMTS13 prevents cleavage of ultra‐large von Willebrand factor multimers, resulting in platelet‐rich microthrombi formation ...
González-Resina R   +6 more
europepmc   +2 more sources

B cell reductive therapy with rituximab in the treatment of rheumatoid arthritis. [PDF]

open access: yes, 2009
The approach to treating autoimmune disorders is currently undergoing a significant change in focus. As therapies are developed that are more precise in targeting the pathogenesis for these diseases, patients experience significantly fewer side effects ...
Sands, Jacob, Tuscano, Joseph M
core   +2 more sources

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner   +59 more
wiley   +1 more source

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