Results 151 to 160 of about 124,392 (280)

Atypical Persistent Pruritic Hyperpigmented Plaques in Adult‐Onset Still's Disease: A Case Report From Uganda

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Atypical Persistent hyperpigmented cutaneous lesions associated with adult‐onset Still's disease. ABSTRACT We report a case of adult‐onset Still's disease (AOSD) in a 30‐year‐old Ugandan man presenting with migratory polyarthralgia, intermittent fever, lymphadenopathy, and atypical persistent pruritic hyperpigmented plaques.
Abdisalam Ahmed Sandeyl   +7 more
wiley   +1 more source

Analysis of Real‐World Data Utilization in the Orphan Drug Approval Process: Focusing on New Drug Marketing Applications Submitted to the FDA

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1340-1349, May 2026.
In the field of rare diseases—where traditional clinical trials are often impractical—real‐world data (RWD) have emerged as a scientifically valid alternative to support regulatory decision making. This study systematically evaluates the utilization of RWD in orphan drug approvals by the FDA Center for Drug Evaluation and Research (CDER) over the past ...
Minji Kim, Eunjin Hong
wiley   +1 more source

Group A β-hemolytic streptococcus causing purpura fulminans: two case reports. [PDF]

open access: yesFront Immunol
Alkhatatbeh A   +10 more
europepmc   +1 more source

Engineering, Expression, Purification, and Application of Glycosaminoglycan‐Specific Antibodies

open access: yesCurrent Protocols, Volume 6, Issue 5, May 2026.
Abstract Cluster of differentiation markers have been transformative for defining cell populations and their functional states, but recent work indicates that finer granularity can be achieved by considering the diverse heparan sulfate structures presented on proteoglycans.
Kheerthana Duraivelan   +7 more
wiley   +1 more source

Leukocytoclastic vasculitis and necrobiotic pulmonary nodules in endoscopic remission of ulcerative colitis

open access: yesJPGN Reports, Volume 7, Issue 2, Page 309-311, May 2026.
Abstract Skin and lung findings, including the rare findings of leukocytoclastic vasculitis (LCV) and necrobiotic pulmonary nodules, are known extraintestinal manifestations (EIMs) of inflammatory bowel disease. However, these rare EIMs have typically been reported as being a sign of active intestinal disease.
Joshua D. Noe   +3 more
wiley   +1 more source

Acute Myocardial Infarction Due to Eltrombopag Therapy in a Patient with Immune Thrombocytopenic Purpura

open access: yesTurkish Journal of Hematology, 2017
Sena Sert, Hasan Özdil, Murat Sünbül
doaj   +1 more source

Diffuse purpuric eruption in a patient with acute myeloid leukemia

open access: yesJAAD Case Reports, 2023
Zoha K. Momin, BS   +4 more
doaj   +1 more source

Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review

open access: yesRespirology Case Reports, Volume 14, Issue 5, May 2026.
This case highlights that ANCA‐associated vasculitis can emerge in patients with chronic airway disease and a history of nontuberculous mycobacterial infection, potentially masquerading as infection‐related inflammation. Early recognition based on extrapulmonary clues (urinary abnormalities and neuropathy) enabled prompt diagnosis and treatment with ...
Hidenori Takahashi   +11 more
wiley   +1 more source

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