Results 71 to 80 of about 198,351 (337)

Tapering thrombopoietin receptor agonists in primary immune thrombocytopenia: Expert consensus based on the RAND/UCLA modified Delphi panel method

Research and Practice in Thrombosis and Haemostasis, 2021
Background Thrombopoietin receptor agonists (TPO‐RAs) are used to treat primary immune thrombocytopenia (ITP). Some patients have discontinued treatment while maintaining a hemostatic platelet count.
Adam Cuker, Jenny M. Despotovic, Rachael F. Grace, Caroline Kruse, Michele P. Lambert, Howard A. Liebman, Roger M. Lyons, Keith R. McCrae, Vinod Pullarkat, Jeffrey S. Wasser, David Beenhouwer, Sarah N. Gibbs, Irina Yermilov, Michael S. Broder   +13 more
doaj   +1 more source

What is new in the management of rapidly progressive glomerulonephritis? [PDF]

, 2015
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, Salama, AD
core   +1 more source

Expansion Microscopy of Synaptic Contacts on the Mauthner Cells of Larval Zebrafish

Bio-Protocol
Because of its genetic tractability and amenability for live imaging, larval zebrafish (Danio rerio) have emerged as a model to study the cellular and synaptic properties underlying behavior.
Sundas Ijaz, Sandra Cárdenas-García, Alberto Pereda   +2 more
doaj   +1 more source

Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. [PDF]

, 2018
Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder which presents with isolated thrombocytopenia and risk of hemorrhage. While most children with ITP promptly recover with or without drug therapy, ITP is persistent or chronic in ...
Bennett, Carolyn M., Breakey, Vicky R., Brown, Travis, Buchanan, George R., Bussel, James B., Crary, Shelley E., Despotovic, Jenny M., Forbes, Peter W., Geddis, Amy, Grace, Rachael F., Haley, Kristina M., Hege, Kerry, Jeng, Michael, Klaassen, Robert J., Lambert, Michele P., Lorenzana, Adonis, Neier, Michelle, Neufeld, Ellis J., Neunert, Cindy, Pastore, Yves D., Rose, Melissa J., Rothman, Jennifer A., Shimano, Kristin A., Thompson, Alexis   +23 more
core   +1 more source

Learning to predict: Neuronal signatures of auditory expectancy in human event-related potentials

NeuroImage, 2021
Learning to anticipate future states of the world based on statistical regularities in the environment is a key component of perception and is vital for the survival of many organisms.
Yonatan I. Fishman, Wei-Wei Lee, Elyse Sussman   +2 more
doaj  

Efficacy and safety of open‐label caplacizumab in patients with exacerbations of acquired thrombotic thrombocytopenic purpura in the HERCULES study

Journal of Thrombosis and Haemostasis, 2019
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life‐threatening autoimmune thrombotic microangiopathy. Caplacizumab, an anti‐von Willebrand Factor Nanobody®, is effective for treating aTTP episodes and is well tolerated.
P. Knoebl, S. Cataland, F. Peyvandi, P. Coppo, M. Scully, J. K. Kremer Hovinga, A. Metjian, J. de la Rubia, K. Pavenski, Jessica Minkue Mi Edou, H. de Winter, F. Callewaert   +11 more
semanticscholar   +1 more source

A companion to the preclinical common data elements for rigor, reproducibility and transparency in basic and translational epilepsy research. A report of the TASK3‐WG1A: Pharmacology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView.
Abstract Rigorous and transparent procedures in preclinical epilepsy research studies are important to permit assessing the reproducibility of their findings and derisk their translation into the clinic. The General Pharmacology Working Group of the ILAE/AES Task Force (TASK3‐WG1A) developed common data elements (CDEs) addressing rigor and transparency
Brian D. Klein, Lauren Harte‐Hargrove, Wenzhu Mowrey, Aristea S. Galanopoulou, Cameron S. Metcalf, Lisa Coles, Patrick A. Forcelli, Anna‐Maria Katsarou, Rudiger Koehling, Karine Leclercq, Heidrun Potschka, TASK3‐WG1A working group   +11 more
wiley   +1 more source

The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact

eLife
Most nervous systems combine both transmitter-mediated and direct cell–cell communication, known as ‘chemical’ and ‘electrical’ synapses, respectively. Chemical synapses can be identified by their multiple structural components.
Sandra P Cárdenas-García, Sundas Ijaz, Alberto E Pereda   +2 more
doaj   +1 more source

Proteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric Disorders

Neural Plasticity, 2016
Decades of research have demonstrated that rapid alterations in protein abundance are required for synaptic plasticity, a cellular correlate for learning and memory.
Matthew E. Klein, Hannah Monday, Bryen A. Jordan   +2 more
doaj   +1 more source

PURPURA HEMORRHAGICA [PDF]

The American Journal of the Medical Sciences, 1905
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openaire   +2 more sources