Results 81 to 90 of about 130,655 (306)
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Hemoporfin, a porphyrin derivative photosensitizer, has been approved for the treatment of port‐wine stain (PWS) in adults. However, its optimal dose for the pediatric population remains unclear. This study aimed to explore appropriate dosing for pediatric patients with PWS through population pharmacokinetics (PopPK) and exposure‐response (ER)
Rong Chen +6 more
wiley +1 more source
Natural ITD statistics predict human auditory spatial perception
eLife, 2020 A neural code adapted to the statistical structure of sensory cues may optimize perception. We investigated whether interaural time difference (ITD) statistics inherent in natural acoustic scenes are parameters determining spatial discriminability.
Rodrigo Pavão +3 more
doaj +1 more source
Rheumatology &Autoimmunity, EarlyView.This review seeks to provide a thorough synthesis of the existing literature on the role of thrombopoietin receptor agonists in the treatment of primary and secondary immune thrombocytopenia, with particular emphasis on the compound Hetrombopag. Abstract Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by a platelet count below
Jiaqi Hu +8 more
wiley +1 more source
To which extend is the "neural code" a metric ? [PDF]
arXiv, 2008 Here is proposed a review of the different choices to structure spike trains, using deterministic metrics. Temporal constraints observed in biological or computational spike trains are first taken into account. The relation with existing neural codes (rate coding, rank coding, phase coding, ..) is then discussed.
arxiv
Translational Biophotonics, EarlyView.Optical Coherence Tomography Angiography in the Assessment of Vulvar Lichen Sclerosus ABSTRACT Vulvar lichen sclerosus is a chronic inflammatory skin condition that leads to scarring and an increased risk of squamous cell carcinoma. It presents clinically as atrophic white patches or plaques, often with associated fissures, erosions, hyperkeratosis ...
Raksha Sreeramachandra Murthy +3 more
wiley +1 more source
New England Journal of Medicine, 1991 BACKGROUND Thrombotic thrombocytopenic purpura is an uncommon disease with a high mortality rate even with current treatment. The cause of the syndrome and its optimal treatment are unknown.
G. Rock +6 more
semanticscholar +1 more source
British Journal of Haematology, EarlyView.The use of rituximab as a pre‐emptive treatment in immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is the current standard of care. However, for patients refractory to rituximab or for those with contraindication, further treatment guidelines are scarce.
Julia Weisinger +4 more
wiley +1 more source
Developmental Medicine &Child Neurology, EarlyView.In children with symptomatic congential CMV, those with polymicrogyria are at an increased risk of developing epilepsy. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16263 Abstract Aim To identify neonatal magnetic resonance imaging (MRI) features that predict the likelihood of children with congenital cytomegalovirus (cCMV ...
George Lawson +7 more
wiley +1 more source