Results 101 to 110 of about 4,220 (193)

SURVIVAL CASE OF PURPURA FULMINANS IN MENINGOCOCCAL SEPTICAEMIA IN AN ADULT WITH TRANSIENT PROTEIN C DEFICIENCY: A CASE REPORT

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
Background: Purpura fulminans (PF) is a rapidly progressive thrombotic disorder affecting neonates and children and adults in which there is haemorrhagic infarction of skin and disseminated intravascular coagulation.
Joaquin Valle Alonso
doaj  

Administration of protein C concentrates in patients without congenital deficit: a systematic review of the literature [PDF]

open access: yes, 2013
Endogenous protein C levels are frequently decreased in septic patients, probably due to increased conversion to activated protein C. Protein C levels inversely correlate with morbidity and mortality of septic patients regardless of age, infecting ...
ALBERTO ZANGRILLO   +6 more
core   +1 more source

Púrpura fulminans asociada con picadura por abejas

open access: yesRevista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2002
Se presenta el caso clínico de un niño de 6 años de edad con púrpura fulminans, secundaria a coagulación intravascular diseminada, asociado con picadura por abejas.
Angela María Acosta A.   +2 more
doaj  

Meningococcal meningitis complicated by septic shock, myocarditis and purpura fulminans

open access: yesAsian Journal of Internal Medicine
Meningococcal disease is a rapidly progressive, life-threatening infection caused by Neisseria meningitidis. Typical presentations include meningitis, septicaemia, or a combination of the two.
H. M. U. A. S. Perera   +2 more
doaj   +1 more source

Protein C in adult patients with sepsis: from pathophysiology to monitoring and supplementation

open access: yesJournal of Anesthesia, Analgesia and Critical Care
Protein C (PC) plays a crucial role in modulating inflammation and coagulation in sepsis. Its anticoagulant and cytoprotective properties are critical in mitigating sepsis-induced coagulopathy, which is associated with high mortality rates.
Irene Coloretti   +10 more
doaj   +1 more source

EHA2024 Hybrid Congress

open access: yes
HemaSphere, Volume 8, Issue S1, June 2024.
wiley   +1 more source

Treatment of necrotizing fasciitis using negative pressure wound therapy in a puppy [PDF]

open access: yes, 2015
A two-month-old German shepherd dog was presented with anorexia, lethargy and left hind limb lameness associated with swelling of the thigh. Clinical findings combined with cytology led to the presumptive diagnosis of necrotizing fasciitis (NF ...
Abma, Eline   +5 more
core   +1 more source

Use of human protein C concentrates in the treatment of patients with severe congenital protein C deficiency

open access: yesBiologics: Targets & Therapy, 2010
Sabine Kroiss, Manuela AlbisettiDivision of Hematology, University Children’s Hospital, Zurich, SwitzerlandAbstract: Protein C is one of the major inhibitors of the coagulation system that downregulate thrombin generation.
Sabine Kroiss, Manuela Albisetti
doaj  

Severe congenital protein C deficiency: the use of protein C concentrates (human) as replacement therapy for life-threatening blood-clotting complications

open access: yesBiologics: Targets & Therapy, 2008
Paul N KnoeblDepartment of Medicine 1, Division Hematology and Hemostasis, Medical University of Vienna, Vienna, AustriaAbstract: The protein C pathway has an important function in regulating and modulating blood coagulation and ensuring patency of the ...
Paul N Knoebl
doaj  

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