Results 21 to 30 of about 76,431 (45)
Hereditary thrombotic thrombocytopenic purpura
Haematologica, 2019 The first description of thrombotic thrombocytopenic purpura (TTP) by Moschowitz was published nearly 100 years ago.[1][1] This was likely to have been an immune-mediated TTP episode and the author described multi organs affected with worsening ...
M. Scully
semanticscholar +1 more source
Henoch-Schönlein Purpura: A Literature Review.
Acta Dermato-Venereologica, 2017 Henoch-Schönlein purpura is the most common childhood vasculitis, but may also affect adults. This article reviews the literature since 2011 on advances in diagnosis, clinical disease manifestations, pathophysiology and treatment of Henoch-Schönlein ...
L. Hetland +3 more
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Growth and morphogenesis of the gastropod shell
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Mollusc shells are emblematic of the morphological diversity in nature. They are important models for understanding the evolution of form; they are all variations on the same basic geometrical groundplan, their shapes can be directly related
Adam B. Johnson +2 more
semanticscholar +1 more source
Biology Letters, 2018 Microplastics are a ubiquitous source of contaminations in marine ecosystems, and have major implications for marine life. Much effort has been devoted to assessing the various effects of microplastics on marine life.
L. Seuront
semanticscholar +1 more source
Haematologica, 2018 Immune-mediated thrombotic thrombocytopenic purpura is characterized by severe thrombocytopenia and microangiopathic hemolytic anemia. It is primarily caused by immunoglobin G type autoantibodies against ADAMTS13, a plasma metalloprotease that cleaves ...
E. Staley +10 more
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Pathophysiology of thrombotic thrombocytopenic purpura.
Blood, 2017 The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic purpura (TTP).
J. E. Sadler
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Blood, 2009 Diagnosis and management of immune thrombocytopenic purpura (ITP) remain largely dependent on clinical expertise and observations more than on evidence derived from clinical trials of high scientific quality.
F. Rodeghiero +19 more
semanticscholar +1 more source
PLoS ONE, 2016 Background and objective Henoch-Schönlein purpura (HSP) is an important cause of chronic kidney disease in children. This meta-analysis identified risk factors associated with renal involvement in childhood HSP. Methods PubMed, Embase, and Web of Science
Han Chan +6 more
semanticscholar +1 more source
Journal of Thrombosis and Haemostasis, 2017 Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic (TE) events, exacerbations and death was studied. Fewer caplacizumab‐treated patients had a major
F. Peyvandi +8 more
semanticscholar +1 more source
ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura.
Annual Review of Medicine, 2015 Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver, and its main function is to cleave von Willebrand factor (VWF) anchored on ...
X. Zheng
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