Results 41 to 50 of about 8,418 (256)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Comparative evaluation of push-out bond strength of AH-Plus, MTA-Fillapex and Epiphany SE root canal sealers: An Ex-Vivo study

Indian Journal of Dental Research, 2022
Background: A successful root canal (RC) treatment depends upon creation of a fluid impervious seal that is commonly built by using a RC sealer along with gutta-percha.
Sagolsem Chandarani, Mohan Gundappa, Zoya Chowdhary, Deepika Singh, Neeti Swarup, Shalabh Mehrotra   +5 more
doaj   +1 more source

Effect of cement type and thickness on push-out bond strength of fiber posts [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2018
Background. This study investigated the effect of the thickness of two resin cements on push-out bond strength of fiber posts to root dentin. Methods. Sixty decoronated single-rooted teeth were endodontically treated. The specimens were then randomly allocated to two groups (n=30); group 1: drill size 90 w, matching the size of fiber posts used; group
Farzaneh Farid, Khadijeh Rostami, Sareh Habibzadeh, MohammadJavad Kharazifard   +3 more
openaire   +3 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Effect of Different Silane Coupling Agents on the Bond Strength between Hydrogen Peroxide-Etched Epoxy-Based- Fiber-Reinforced Post and Composite Resin Core

Dentistry Journal, 2023
The aim of the study was to evaluate the effect of various silane coupling agents on the micro-push-out bond strength between a hydrogen peroxide-etched epoxy-based fiber-reinforced post and composite resin core.
Sarah Adwani, Emad Elsubeihi, Ahmad Zebari, May Aljanahi, Keyvan Moharamzadeh, Haitham Elbishari   +5 more
doaj   +1 more source

Impact of Heating Exposure on the Micro-Push-Out Bond Strength of Bioceramic Sealers

International Journal of Dentistry, 2023
Introduction. The aim of this study was to evaluate the effect of heating of bioceramic and epoxy resin-based sealers on their micro-push-out bond strength (BS) to root canal dentin. Methods. After criterial selection, 30 human teeth were decoronated and 1-mm thick slices (n = 60) were obtained perpendicularly along tooth axis, from cervical and middle
Guilherme Rodrigues Cândido Lopes, Maria Eduarda Paz Dotto, Lincon Hideo Nomura, Daniela Peressoni Vieira Schuldt, Lucas da Fonseca Roberti Garcia, Cleonice da Silveira Teixeira   +5 more
openaire   +3 more sources

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Comparison of Fiber Post Bond Strength to Root Canal Dentin Following Chlorhexidine and Carbodiimide Pretreatment [PDF]

Journal of Mashhad Dental School
Background: Fiber post placement is a common practice for restoring endodontically treated teeth with weakened roots. The use of matrix metalloproteinase (MMP) inhibitors has been suggested to enhance the bond strength between fiber posts and root canal ...
Abdolrahim Davari, Farnaz Farahat, Bita Ahadi   +2 more
doaj   +1 more source