Results 61 to 70 of about 8,230 (180)

Acute generalized exanthematous pustulosis in a patient with plaque psoriasis

Saudi Journal of Medicine and Medical Sciences, 2014
Acute generalized exanthematous pustulosis (AGEP) is an acute febrile drug eruption characterized by sudden occurrence of numerous, non-follicular, pinhead-sized pustules. This usually occurs 3-5 days after the commencement of treatment.
Khalid A Al Hawsawi, Hawazin D Jan, Ali A Al Raddadi, Aymen H Alharbi, Mazin M Al Jabri, Mohammed B Satti   +5 more
doaj   +1 more source

Severe generalized pustular psoriasis complicated with staphylococcal toxic shock syndrome treated with spesolimab and antibiotics

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Spyridon Gkalpakiotis, Jan Hugo, Natalie Michalik, Robert Zajicek, Cecilie Stonova, Bohumil Bakalar   +5 more
wiley   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

"ACUTE GENERALIZED PUSTULAR PSORIASIS AND IDIOPATHIC HYPOPARATHYROIDISM IN AN ADOLESCENT GIRL" [PDF]

Acta Medica Iranica, 2004
Generalized pustular psoriasis with hypoparathyroidism has been reported previously often as a post thyroidectomy syndrome with hypoalbuminemia and hypocalcemia. But reports on association of pustular psoriasis with idiopathic hypoparathyroidism are very
Sh.S.Ashkevari A.Maboodi
doaj   +1 more source

Methotrexate and Adalimumab Combination Efficacy in 4-year-old Child with Generalized Pustular Psoriasis: Case Study

Вопросы современной педиатрии
Background. Generalized pustular psoriasis management in children is a topical issue due to limited use and efficacy of traditional immunodepressants, absence of registered genetically engineered biologic drugs.
Nikolay N. Murashkin, Mariya A. Leonova, Alexandra Yu. Kulishova, Anna V. Skibitskaya, Alexandr I. Materikin, Roman V. Epishev, Dmitry V. Fedorov, Roman A. Ivanov, Ekaterina S. Pavlova, Leonid A. Opryatin   +9 more
doaj   +1 more source

A Serum N‐Glycan Ratio Associated With Disease Severity and Treatment Response in Psoriasis

The Journal of Dermatology, Volume 53, Issue 8, Page 1090-1098, August 2026.
ABSTRACT Psoriasis is a chronic, immune‐mediated inflammatory disease with heterogeneous manifestations. Reliable biomarkers reflecting disease severity and treatment response remain limited. Glycans—carbohydrate structures attached to proteins and lipids—play key roles in biological processes, contributing to functional specificity.
Kentarou Nishimura, Noritaka Oyama, Takumi Hasegawa, Hiroshi Kasamatsu, Takenao Chino, Takahiro Tokunaga, Kiyoshi Higashi, Koichi Saito, Keita Yamada, Minoru Hasegawa   +9 more
wiley   +1 more source

Paradoxical reaction to IL-17A inhibitor: a case report and literature review

Frontiers in Medicine
ObjectiveA case of pustular psoriasis after treatment with secukinumab in a patient with plaque psoriasis is reported, which is the first case in China. To summarize the clinical characteristics of patients who developed the rare paradoxical reaction and
Jingyu Ren, Linjun Deng, Shuping Guo, Hongye Liu   +3 more
doaj   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, Volume 81, Issue 8, Page 2815-2832, August 2026.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Von Zumbusch’s pustular psoriasis associated with oral terbinafine

Journal of Dermatology and Dermatologic Surgery, 2017
Adverse skin reactions have been reported in 2.7% of patients receiving oral terbinafine. Less common but life-threatening reactions include acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson syndrome, toxic epidermal necrolysis ...
Naoufal Hjira, Adil Boudhas, Rachid Frikh, Noureddine Baba, Mohammed Oukabli, Mohammed Boui   +5 more
doaj   +1 more source