Results 81 to 90 of about 15,060 (265)

Cryptococcid Sweet Syndrome in the Setting of Hydralazine‐Induced ANCA Vasculitis: A Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Acute febrile neutrophilic dermatosis, also known as Sweet syndrome, is an inflammatory skin condition characterized by the rapid onset of painful, erythematous plaques or nodules with neutrophilic infiltrate on histology. Rarely, acellular bodies surrounded by vacuolated spaces have been noted within the neutrophilic infiltrate, mimicking ...
Jenna Vroman, Pelin Sagut, Kathryn Lynam, Amanda Ederle, Laura Winterfield   +4 more
wiley   +1 more source

Acute generalized exanthematous pustulosis after COVID‐19 treatment with hydroxychloroquine

Dermatologic Therapy, 2020
Dear Editor, Hydroxychloroquine (HCQ) was recently suggested for both chemoprophylaxis and treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, data on the safety profile of HCQ in coronavirus disease-19 (COVID-19)
N. Litaiem, K. Hajlaoui, Manel Karray, M. Slouma, F. Zeglaoui   +4 more
semanticscholar   +1 more source

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami, Yukari Okubo, Satomi Kobayashi, Natsuko Kikuta, Yoshiumi Ouchi, Kenta Shishido, Tadashi Terui   +6 more
wiley   +1 more source

Characterization of amoxicillin‐ and clavulanic acid‐specific T cells in patients with amoxicillin‐clavulanate–induced liver injury [PDF]

, 2015
Drug‐induced liver injury (DILI) frequently has a delayed onset with several human leukocyte antigen (HLA) genotypes affecting susceptibility, indicating a potential role for the adaptive immune system in the disease.
Abajo, Bomarrito, Britschgi, Cavani, Daly, Danan, Donaldson, Fontana, Jenkins, Kindmark, Li, Lucena, Lucena, Maria, Mauri-Hellweg, Metushi, Monshi, Mudnakudu Nagaraju, Naisbitt, Nattrass, O'Donohue, Pichler, Pichler, Sabat, Schaid, Singer, Spraggs, Stephens, Wu, Wu, Wuillemin, Wuillemin, Yanaba, Yanaba   +33 more
core   +1 more source

Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Tadashi Terui, Yukari Okubo, Satomi Kobayashi, Akimichi Morita, Shinichi Imafuku, Yayoi Tada, Masatoshi Abe, Bruce Strober, Melinda Gooderham, Wendy Zhang, Junichiro Shimauchi, Masafumi Yaguchi, Takeshi Kimura, Ryuichi Ogawa, Hamid Amouzadeh, Masamoto Murakami   +15 more
wiley   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Erythrokeratodermia‐Cardiomyopathy Syndrome: Expanding the DSP Mutational Spectrum Beyond Proline Substitutions

Pediatric Dermatology, EarlyView.
ABSTRACT Erythrokeratodermia cardiomyopathy (EKC) syndrome is a rare autosomal dominant disorder characterized by generalized erythrokeratoderma and progressive dilated cardiomyopathy, caused by pathogenic variants in the SR6 domain of desmoplakin (DSP).
Sepideh Hamzehlou, Ryland D. Mortlock, Caroline Echeandia‐Francis, Jing Zhou, Chao Xing, Nnenna G. Agim, Keith A. Choate, Donald A. Glass II   +7 more
wiley   +1 more source

Microscopic Examination of Nail Clippings from Patients with Palmoplantar Pustulosis

Dermatopathology, 2019
This study describes the clinical characteristics and microscopic findings of nails from 25 patients with palmoplantar pustulosis. Methods: This is a cross-sectional study of adult patients with clear-cut palmoplantar pustulosis. Onychodystrophy severity
Anber Ancel Tanaka, Betina Werner, Cassia Farris, Cassio Tornesy   +3 more
doaj   +1 more source

A case of chronic recurrent multifocal osteomyelitis associated with Crohn's disease [PDF]

, 2015
Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-
De Baets, Frans, Dehoorne, Jo, Van Biervliet, Stephanie, van Ommen, Christi, Van Winckel, Myriam, Vande Velde, Saskia   +5 more
core  

In vitro effects of zinc on the cytokine production from peripheral blood mononuclear cells in patients with zinc allergy. [PDF]

, 2015
Metals, such as nickel, cobalt, chromium and zinc, are ubiquitous in the environment. Systemic reactions, including hand dermatitis and generalized eczematous reactions, can be caused by the dietary ingestion of metals.
AS Prasad, BL Vallee, CS Jensen, H Falsafi Amin, JP Thyssen, JT Minang, KL Chang, L Borg, L Rink, N Saito, N Wellinghausen, N Wellinghausen, S Cunningham-Rundles, SE Jacob, T Fisher, T Ido, T Sakai, T Yanagi, T Yanagi, Y Ito, Y Yoshihisa   +20 more
core   +2 more sources