Results 221 to 230 of about 7,358,659 (287)

Correction: Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation. [PDF]

Cell Death Dis
Zhang J, Chen L, Xu Q, Zou Y, Sun F, Zhou Q, Luo X, Li Y, Chen C, Zhang S, Xiong F, Yang P, Liu S, Wang CY.   +13 more
europepmc   +1 more source

Put in a Box [PDF]

, 2018
Rammage, Libbie
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Lived Experiences of Men Working in Both White-Collar and Blue-Collar Jobs: A Systematic Literature Review. [PDF]

Am J Mens Health
Omolewa P, Bressan J, Noureddine N, Adedipe A.   +3 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Integrated laboratory workflow for proton exchange membrane fuel cell fabrication and testing. [PDF]

Sci Rep
Hesham H, Abdel Rahman M, Bassioni G, Swief RA, Ezzat M, Helmy S, Elbehairy NM.   +6 more
europepmc   +1 more source

How the Isthmus of Panama put ice in the Arctic [PDF]

, 2004
Haug, Gerald H., Keigwin, Lloyd D., Tiedemann, Ralf   +2 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A qualitative study exploring concepts and attitudes of guinea pig producers in rural parishes of Pichincha, Ecuador: The need for a one health-one welfare approach to enhance production practices. [PDF]

One Health
Fowler H, Faulkner G, Donoso G, Fuentes O, Pairis-Garcia M, Rhea S.   +5 more
europepmc   +1 more source

Put Križa [PDF]

, 2012
Alka Pintarić
core