Results 11 to 20 of about 4,265 (181)

Effectiveness of paint psoralen and ultraviolet-A in alopecia areata – Our experience in the national skin center

Indian Journal of Dermatology, 2020
Background: Alopecia areata (AA) is usually a benign cause of patchy hair loss that often resolves within a few weeks to months. Most treatment modalities are ineffective in the treatment of severe AA.
Lucinda Siyun Tan, Melissa Mei Hsia Chan, Daryl Jian An Tan, Joyce Siong See Lee, Wei-Sheng Chong   +4 more
doaj   +1 more source

Quality of Life, Anxiety, and Depression in Patients With Early-Stage Mycosis Fungoides and the Effect of Oral Psoralen Plus UV-A (PUVA) Photochemotherapy on it

Frontiers in Medicine, 2020
Background: Little is known about psychological discomfort and quality of life (QoL) in early stage mycosis fungoides (MF) and the effect of psoralen plus UV-A (PUVA) on it.Objective: To evaluate QoL, anxiety, and depression with validated instruments in
Thomas Graier, Regina Fink-Puches, Stephanie Porkert, Roland Lang, Sophie Pöchlauer, Gudrun Ratzinger, Adrian Tanew, Sylvia Selhofer, Paul-Gunther Sator, Angelika Hofer, Alexandra Gruber-Wackernagel, Franz J. Legat, Pablo Augusto Vieyra-Garcia, Franz Quehenberger, Peter Wolf   +14 more
doaj   +1 more source

Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet A (PUVA) sensitivity.

PLoS ONE, 2013
BackgroundThere are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis. Psoralens are metabolised by cytochrome P450 enzymes (P450), and we hypothesised that
Yusuf Y Deeni, Sally H Ibbotson, Julie A Woods, C Roland Wolf, Gillian Smith   +4 more
doaj   +1 more source

Comparison of Efficacy of Localized Narrow-Band UVB Therapy Versus Localized PUVA Therapy in Chronic Hand Eczema

Nepal Journal of Dermatology, Venereology & Leprology, 2023
Introduction: Hand eczema is a type of dermatitis largely confined to the hands. Narrowband UVB (NBUVB) appears to be as effective as topical PUVA therapy in the treatment of chronic hand dermatitis.
Dhan Keshar Khadka, Sudha Agrawal, Arpana Rijal, Samir Shrestha   +3 more
doaj   +3 more sources

Phototherapy of extragenital white spot disease

Vestnik Dermatologii i Venerologii, 2017
Objective. To study the effectiveness of UVA1therapy and PUVA therapy in patients with extragenital lichen sclerosus. Materials and methods. Effectiveness of the phototherapy methods was studied in 12 patients with extragenital lichen sclerosus (8 women,
B. A. Volnukhin, L. F. Znamenskaya, I. A. Kappusheva, N. L. Muradyan, A. S. Dvornikov   +4 more
doaj   +1 more source

Efficiency of phototherapy in patients with mycosis fungoides: preliminary results of a comparative non-randomized study

Vestnik Dermatologii i Venerologii, 2020
Clinical reasoning. There is a need to optimize the use of UV-B-311 nm and PUVA-therapy in patients with mycosis fungoides to determine the duration of the treatment regimen, the number of sessions per week, and ultraviolet irradiation regimen.
A. E. Karamova, M. B. Zhilova, L. F. Znamenskaya, A. A. Vorontsova   +3 more
doaj   +1 more source

8-Methoxypsoralen Plus Ultraviolet A Reduces the Psoriatic Response to Imiquimod in a Murine Model

Acta Dermato-Venereologica, 2018
The effects of 8-Methoxypsoralen plus ultraviolet A (PUVA) or ultraviolet B (UVB) alone on imiquimod-induced psoriasis were examined in a mouse model.
Nitesh Shirsath, Karin Wagner, Simone Tangermann, Michaela Schlederer, Christian Ringel, Lukas Kenner, Bernhard Brüne, Peter Wolf   +7 more
doaj   +1 more source

Accidental PUVA burns, vitiligo and atopic diathesis resulting in prurigo nodularis: a logical but undocumented rarity Prurigo nodular induzido por queimaduras acidentais por PUVA, vitiligo e diátese atópica: uma raridade lógica, mas não documentada

Anais Brasileiros de Dermatologia, 2012
Vitiligo is a dreaded disease in India due to its social and cultural consequences. PUVA and PUVAsol are the main treatment modalities for vitiligo vulgaris.
Shyam Bhanushankar Verma, Uwe Wollina
doaj   +1 more source

Phototherapy as a First Line Treatment for Mycosis Fungoides: A 10-year Retrospective Study

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2019
Introduction: Phototherapy, particularly psoralen plus ultraviolet A (PUVA) and narrowband ultraviolet B (nbUVB), is a mainstay in the treatment of Mycosis Fungoides (MF).
Alexandra Azevedo, Iolanda Fernandes, Renata Cabral, Margarida Lima, Isabel Amorim, Manuela Selores   +5 more
doaj   +1 more source

Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis.

PLoS ONE, 2014
Photo-activation of psoralen with UVA irradiation, referred to as PUVA, is used in the treatment of proliferative skin disorders. The anti-proliferative effects of PUVA have been largely attributed to psoralen intercalation of DNA, which upon UV ...
Wenle Xia, David Gooden, Leihua Liu, Sumin Zhao, Erik J Soderblom, Eric J Toone, Wayne F Beyer, Harold Walder, Neil L Spector   +8 more
doaj   +1 more source