Results 251 to 260 of about 307,273 (315)

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Enhancement of Piezoelectric Performance in PVDF via ZnO Doping and Its Application in Wearable Real-Time Monitoring of Human Radial Pulse. [PDF]

Biosensors (Basel)
Zhu H, Guo X, Liu Q, Zhang Q.
europepmc   +1 more source

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

Advanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang, Yuxiang Ren, Shofarul Wustoni, Atheer Alqatari, Adel Hama, Yazhou Wang, Long Chen, Jessica Parrado Agudelo, Luca Salvigni, Keying Guo, Ashraf Dada, Stefan T. Arold, Raik Grünberg, Sahika Inal   +13 more
wiley   +1 more source

Carboxylated Poly(vinylidene fluoride) Copolymer: A Facile Route to Improve Ultrafiltration Membrane Properties for Aqueous Filtration. [PDF]

Membranes (Basel)
Jiang Y, Zhao Z, Yu X, Cheng Q, Zou S, Zeng Y, Huang Q, Zhu Z, Zhu W, Zhu L, Zhu B.   +10 more
europepmc   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Nanochitin as Binder in Li-Ion Battery Anodes Enabling Aqueous Processing and Superior Solid Electrolyte Interphase. [PDF]

ACS Appl Mater Interfaces
Sandra AP, Arumughan V, Teixeira Polez R, Lindgren F, Hahlin M, Tao H, Österberg M, Kontturi E, Wreland Lindström R.   +8 more
europepmc   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Fabrication of Magnetically and Photothermally Functionalized Materials Based on Corn Stalk Pith Framework for Oil-Water Separation. [PDF]

Polymers (Basel)
Cui Y, Shu X, Cui B, Ding J, Dai W, Yang C, Wang W.   +6 more
europepmc   +1 more source

Evaluating Thioredoxin-Mediated CF_oCF₁ Reduction Using an In Vitro Thylakoid Assay. [PDF]

Bio Protoc
Sekiguchi T, Yoshida K, Hisabori T.
europepmc   +1 more source

Eco-Functional PVDF Mixed Matrix Membranes: Characterization and Regeneration in Natural Rubber Skim Latex Purification. [PDF]

Polymers (Basel)
Gayatri R, Iqbal RM, Taweepreda W, Zulkifli M, Yahaya ANA.   +4 more
europepmc   +1 more source