Results 71 to 80 of about 1,690 (161)

Device development guided by user satisfaction survey on auricular vagus nerve stimulation

Current Directions in Biomedical Engineering, 2016
Development of wearable point-of-care medical devices faces many challenges. Besides technological and clinical issues, demands on robustness, miniaturization, and user interface design are of paramount importance.
Kampusch Stefan, Kaniusas Eugenijus, Thürk Florian, Felten Dorian, Hofmann Ibolya, Széles Jozsef C.   +5 more
doaj   +1 more source

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J. Michael, Vincent Joseph, Richard Kinkead   +5 more
wiley   +1 more source

Brain‐Wide Connectivity and Topographic Organization of Leptin Receptor Neurons in the Dorsomedial Hypothalamus

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Whole‐brain input–output mapping reveals that DMDLepRb and DMHLepRb neurons share a highly conserved global connectivity architecture yet exhibit local connection biases: DMDLepRb neurons preferentially integrate arousal and defensive signals, whereas DMHLepRb neurons favor viscerosensory and metabolic inputs, uncovering a principle of conserved global
Yaxin Hao, Xiang Zhang, Danyang Zhao, Haixing Zhong, Yongqiang Chen, Heming Li, Minghui Ren, Mengchu Zhu, Fang Yuan   +8 more
wiley   +1 more source

Localized pigmented villonodular synovitis of posterior compartment of the knee

Journal of Orthopaedic Surgery, 2017
Pigmented villonodular synovitis (PVNS) is an uncommon entity involving articular or extra-articular tissues and maybe localized or diffuse in extent. The knee is by far the commonest joint to get involved.
Anshu Shekhar, Shantanu Sudhakar Patil, Chandrashekhar Dixit, Sachin Ramchandra Tapasvi   +3 more
doaj   +1 more source

Longterm results of surgical treatment of pigmented villonodular synovitis of the knee

Acta Orthopaedica et Traumatologica Turcica, 2020
Objectives: The aim of this study was to evaluate the long-term results of total synovectomy in pigmented villonodular synovitis of the knee (PVNS). \r\nMethods: Open total synovectomy was performed for 19 patients (9 men, 10 women; mean age: 42.8 years)
Orhan Akinci, Yavuz Akalin, Mustafa Incesu, Ahmet Eren   +3 more
doaj   +1 more source

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

Postmortem Evidence of CRH Neuron Reduction in Narcolepsy Without Cataplexy With Borderline Hypocretin‐1 Levels

Journal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan, Suzan Linssen, Rolf Fronczek, Lucie Barateau, Christelle Peyron, Yves Dauvilliers   +5 more
wiley   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, Volume 13, Issue 54, 28 September 2026.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Diffuse‐Type Tenosynovial Giant Cell Tumor of the Hip With Acetabular Bone Involvement: A Case Report With Radiologic‐Pathologic Correlation

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Diffuse‐type tenosynovial giant cell tumor (D‐TGCT) is an uncommon synovial neoplasm. Hip involvement is rare and may be difficult to recognize because symptoms are nonspecific and osseous erosion can mimic more aggressive infectious, inflammatory, or neoplastic processes.
Wang Quanbing, Xing Huanhuan, Zhang Xing, Yang Tao, Zhang Jun, Zhu Lei, Li Kai, Luo Lei, Ao Feng, Yang Wei   +9 more
wiley   +1 more source