Results 161 to 170 of about 159,479 (261)

Oral Helicobacter pylori: a scoping review and pilot study on the PCR-culture detection paradox. [PDF]

open access: yesClin Oral Investig
Miller E   +8 more
europepmc   +1 more source

Clinical trial: The Effect on Intragastric pH and Pharmacokinetics of the PCAB Linaprazan Glurate in Healthy Subjects After Repeat‐Dose Administration for up to 14 Days

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this Phase 1 study, linaprazan glurate (LG) demonstrated rapid onset of intragastric acid suppression, achieving a pH > 4 within 10 to 60 min, and maintained pH control, with a 24‐h pH > 4 holding time ratio above 95% at 50 mg and 75 mg twice‐daily doses. AUC and Cmax of linaprazan, the main metabolite of LG, increased in proportion to LG dose.
Kajsa Larsson   +7 more
wiley   +1 more source

The TOP‐GERD Trial: Comparative Efficacy of Tegoprazan Versus Pantoprazole in the Treatment of Erosive Oesophagitis in a Non‐Asian Population

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.
José M. Remes‐Troche   +9 more
wiley   +1 more source

Gastric Cancer Mortality in a High Incidence Area: Long-term follow-up of Helicobacter pylori-related Precancerous Lesions in the General Population [PDF]

open access: yes
BACKGROUND: Due to a lack of clear criteria for recognizing subjects at risk of progression to gastric cancer (GC), this cohort study seeks to identify predictors of GC death in a high-risk population. METHODS: During 2000-2001, 1011 randomly selected
نیک منش, آرش   +11 more
core  

Anatomy and Histology of the Midgut of Atopozelus opsimus (Heteroptera: Reduviidae)

open access: yesActa Zoologica, EarlyView.
ABSTRACT Atopozelus opsimus Elkins, 1954 (Heteroptera: Reduviidae) preys on forest and agricultural pests but also feeds on extrafloral nectar; however, its alimentary canal is poorly understood. The aim was to describe the anatomy and histology of the A. opsimus midgut. The alimentary canal of female and male A.
Bruna Silva Lisboa   +6 more
wiley   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff   +3 more
wiley   +1 more source

Short stature and Helicobacter pylori infection in Italian children: prospective multicentre hospital based case–control study. (I.F. 5.143)

open access: yes, 1998
Helicobacter pylori is mainly acquired in childhood,1 but the diseases associated with such infection remain unknown. Scottish and Italian schoolchildren infected with H pylori showed reduced growth in height,2,3 and H pylori gastritis was found in 55 ...
E. Chiorboli   +6 more
core  

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