Results 231 to 240 of about 59,828 (388)

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

open access: yesSmall Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai   +9 more
wiley   +1 more source

Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiology, clinically resembling pancreatic cancer, yet uniquely responsive to steroid treatment.
Vladyslav Dovhalyuk   +5 more
wiley   +1 more source

Gastric acid response to pylorus ligation in rats: is gastrin or histamine involved? [PDF]

open access: bronze, 1982
J. Alumets   +6 more
openalex   +1 more source

Efficacy and Safety of Vonoprazan and High‐Dose Amoxicillin Dual Therapy for Rescue Treatment of Helicobacter pylori Infection: A Multicenter Randomized Controlled Trial

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Vonoprazan and amoxicillin dual therapy has demonstrated favorable efficacy in the initial treatment of Helicobacter pylori (H. pylori) infection. This study aimed to evaluate the efficacy and safety of vonoprazan and high‐dose amoxicillin (VHA) dual therapy for H. pylori rescue treatment. Methods This was an open label, multicenter,
Ju Zhang   +13 more
wiley   +1 more source

Totally laparoscopic pylorus-preserving gastrectomy for early gastric cancer in the middle stomach: technical report and surgical outcomes

open access: yesGastric Cancer, 2014
K. Kumagai   +9 more
semanticscholar   +1 more source

Effectiveness of Gastric Cancer Endoscopic Screening in Intermediate‐Risk Countries—A Systematic Review and Meta‐Analysis

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Gastric cancer remains a major cause of cancer‐related mortality in intermediate‐risk countries. Although endoscopic screening is widely implemented in high‐risk regions, its effectiveness and economic viability in intermediate‐risk settings remain uncertain.
M. B. Mourato   +6 more
wiley   +1 more source

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