Results 81 to 90 of about 30,369 (259)
Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source
Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
wiley +1 more source
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari +3 more
wiley +1 more source
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley +1 more source
Pylorus-Preserving Pancreaticoduodenectomy
In patients with resectable adenocarcinoma of the head of the pancreas, pancreaticoduodenectomy serves as the cancer-directed operation of choice. The pylorus-preserving modification of pancreaticoduodenectomy is commonly performed in this setting. Reconstruction of the gastrointestinal tract following pylorus-preserving pancreaticoduodenectomy can be ...
openaire +2 more sources
Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood +3 more
wiley +1 more source
Opiates, the Pylorus, and Gastroparesis [PDF]
Michael Camilleri, Kenton M. Sanders
openaire +2 more sources
Abstract Foreign body (FB) ingestion is a relatively frequent occurrence in the pediatric population with multiple potential sequelae. Appropriate intervention may range from urgent endoscopic retrieval to watchful waiting, with multiple variables influencing the decision.
Oren Ledder +18 more
wiley +1 more source

