Results 11 to 20 of about 14,651 (207)

Reduced Non-Specific Binding of Super-Resolution DNA-PAINT Markers by Shielded DNA-PAINT Labeling Protocols. [PDF]

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Conventional immunohistochemistry labeling with oligonucleotide conjugated secondary antibodies can lead to significant non‐specific uptake across biological cells and is especially prominent within the nucleus. By adding a pre‐incubation step with fully or partially complementary strands and increasing the ionic strength of the buffer this non ...
Lučinskaitė E, Bokhobza AFE, Stannard A, Meletiou A, Estell C, West S, Michele LD, Soeller C, Clowsley AH.   +8 more
europepmc   +3 more sources

Solution Structure and Relaxivity of Ln‐DOTXAZA Derivatives

European Journal of Inorganic Chemistry, Volume 2022, Issue 32, November 17, 2022., 2022
Gd‐Based contrast agents (GBCAs) are essential reagents in clinical diagnosis via MRI. We report four members of the DOTXAZA series, which are valuable scaffolds for the assembly of new GBCAs with improved relaxivity and tailored pharmacokinetic or targeting properties by Cu‐catalyzed alkyne‐azide cycloaddition (CuAAC).
Malte Holzapfel, Torben Baldau, Svenja Kerpa, Gianmarco Guadalupi, Bing Qi, Yang Liu, Wolfgang J. Parak, Wolfgang Maison   +7 more
wiley   +1 more source

Research trends analysis of chronic hepatitis C versus nonalcoholic fatty liver disease: A literature review text‐mining analysis of publications

Health Science Reports, Volume 5, Issue 6, November 2022., 2022
Abstract Background Hepatits C virus (HCV) rates have lowered due to direct‐acting antiviral treatment. Nonalcoholic steatohepatitis (NASH)/nonalcoholic fatty liver disease (NAFLD) is rising with no available therapy. We employed text‐mining to analyze trends in HCV and NAFLD research from the past two decades.
Eyal Klang, Shelly Soffer, Lee Alper, Orit Shimon, Yiftach Barash, Yana Davidov, Mariya Likhter, Oranit Cohen‐Ezra, Gil Ben Yakov, Ziv Ben‐Ari   +9 more
wiley   +1 more source

Sustainable university entrepreneurship: Revisiting firm growth patterns

Business Strategy and the Environment, Volume 31, Issue 4, Page 1334-1346, May 2022., 2022
Abstract Previous research on the firm growth of the university spin‐offs (USOs) and its drivers yields inconclusive results. Recently, the literature on the high‐growth firms (HGFs) has relied on regression quantile methods to study how the effects of growth determinants may differ along the firm growth distribution. This study builds a bridge between
Sara Fernández‐López, David Rodeiro‐Pazos, María Jesús Rodríguez‐Gulías, Manuel Anxo Nogueira‐Moreiras   +3 more
wiley   +1 more source

Trends in inflammatory bowel disease treatment in the past two decades‐a high‐level text mining analysis of PubMed publications

United European Gastroenterology Journal, Volume 9, Issue 9, Page 1019-1026, November 2021., 2021
Abstract Aim Many therapeutic options for inflammatory bowel disease (IBD) emerged during the last 2 decades, along with the rise in disease prevalence and incidence. We aimed at assessing the published literature on different treatment options in that period.
Eyal Klang, Yiftach Barash, Shelly Soffer, Eyal Shachar, Adi Lahat   +4 more
wiley   +1 more source

N‐Heterocyclic Silylene Main Group Element Chemistry: Adduct Formation, Insertion into E−X Bonds and Cyclization of Organoazides

European Journal of Inorganic Chemistry, Volume 2021, Issue 6, Page 548-561, February 12, 2021., 2021
Investigations concerning the reactivity of the N‐heterocyclic silylene Dipp2NHSi (1, 1,3‐bis(2,6‐diisopropylphenyl)‐1,3‐diaza‐2‐silacyclopent‐4‐en‐2‐ylidene) towards selected group three compounds AlI3, E(C6F5)3 (E=B, Al), elemental halides X2 (X=Br, I), tin chlorides Ph2SnCl2 and Me3SnCl, halocarbons PhCH2‐X (X=Cl, Br) and Me−I, as well as ...
Mirjam J. Krahfuss, Udo Radius
wiley   +1 more source

PYMES, RESPONSABILIDAD SOCIAL Y DESARROLLO SOSTENIBLE

InterSedes, 2020
En el presente artículo se identifican y analizan las acciones o actividades concretas que realizan las pymes en materia de responsabilidad social y empresarial que puedan facilitar el desarrollo sostenible, de tal forma que, conociéndolas, se puedan implementar programas de capacitación y orientación en favor de ellas en esta temática.
Campos Campos, Diego, Bermúdez Carrillo, Luis Alberto   +1 more
openaire   +5 more sources

INVESTIGANDO A LAS PYMES

Revista FACES, 2022
El propósito de este artículo es presentar hallazgos obtenidos en el estudio: La Resolución de Problemas y la Producción de Conocimiento Científico y Tecnológico en las Pequeñas y Medianas Empresas Afiliadas a la Cámara de Pequeños y Medianos Industriales y Artesanos del Estado Carabobo, cuyo objetivo fue investigar su historia, su estructura y su ...
Zoraida Linárez, Josefina Toro
openaire   +1 more source

La dimensión social en el modelo socioeconómico de las organizaciones: Un estudio de la Pyme de México

Mercados y Negocios, 2016
El nuevo ambiente de los negocios, que caracteriza al actual siglo, exige a las organizaciones, principalmente a las pequeñas y medianas empresas (PYME), un redireccionamiento de sus estrategias para adecuarlas al nuevo entorno empresarial que presenta ...
Gonzalo Maldonado Guzmán, Gabriela Citlalli López Torres, Sandra Yesenia Pinzón Castro   +2 more
doaj   +3 more sources

Medición del clima organizacional en una Pyme del sector servicios de la región centro de Hidalgo

Revista Geon, 2020
En los últimos años, se han incrementado las Pymes, principalmente las del sector servicios, las cuales ofrecen innumerables oportunidades para estimular el crecimiento y el empleo en un país. Sin embargo, pese a que las Pymes son el pilar fundamental de
Jocelyn Estrella Rodríguez Martínez, Enrique Martínez Muñoz, Danae Duana Avila, Tirso Javier Hernández Gracia   +3 more
doaj   +1 more source