Results 11 to 20 of about 13,238 (225)
El desarrollo empresarial pyme se configura como una apuesta efectiva para el avance competitivo regional; desde la articulación empresa-universidad se oferta una forma diferente de acercarse al mercado y a los proveedores abaratando costos, compartiendo riesgos y garantizando la respuesta al consumidor final al mejor costo posible, como una ilusión ...
López Orozco, Gloria Mercedes +2 more
openaire +4 more sources
Clustering Properties of Neuronal Ryanodine Receptor 2 and Remodeling in the APP/PS1 Mouse Model of Alzheimer's Disease. [PDF]
ABSTRACT Aim The ryanodine receptor (RyR2) is an intracellular Ca2+ release channel which mediates numerous cellular functions across different tissues. Dysregulation of RyR2 channel activity leads to pathological Ca2+ release, which often underlies disrupted cellular signaling in disease states.
Munro ML +8 more
europepmc +2 more sources
Reduced Non-Specific Binding of Super-Resolution DNA-PAINT Markers by Shielded DNA-PAINT Labeling Protocols. [PDF]
Conventional immunohistochemistry labeling with oligonucleotide conjugated secondary antibodies can lead to significant non‐specific uptake across biological cells and is especially prominent within the nucleus. By adding a pre‐incubation step with fully or partially complementary strands and increasing the ionic strength of the buffer this non ...
Lučinskaitė E +8 more
europepmc +3 more sources
Solution Structure and Relaxivity of Ln‐DOTXAZA Derivatives
Gd‐Based contrast agents (GBCAs) are essential reagents in clinical diagnosis via MRI. We report four members of the DOTXAZA series, which are valuable scaffolds for the assembly of new GBCAs with improved relaxivity and tailored pharmacokinetic or targeting properties by Cu‐catalyzed alkyne‐azide cycloaddition (CuAAC).
Malte Holzapfel +7 more
wiley +1 more source
Abstract Background Hepatits C virus (HCV) rates have lowered due to direct‐acting antiviral treatment. Nonalcoholic steatohepatitis (NASH)/nonalcoholic fatty liver disease (NAFLD) is rising with no available therapy. We employed text‐mining to analyze trends in HCV and NAFLD research from the past two decades.
Eyal Klang +9 more
wiley +1 more source
Sustainable university entrepreneurship: Revisiting firm growth patterns
Abstract Previous research on the firm growth of the university spin‐offs (USOs) and its drivers yields inconclusive results. Recently, the literature on the high‐growth firms (HGFs) has relied on regression quantile methods to study how the effects of growth determinants may differ along the firm growth distribution. This study builds a bridge between
Sara Fernández‐López +3 more
wiley +1 more source
Abstract Aim Many therapeutic options for inflammatory bowel disease (IBD) emerged during the last 2 decades, along with the rise in disease prevalence and incidence. We aimed at assessing the published literature on different treatment options in that period.
Eyal Klang +4 more
wiley +1 more source
Investigations concerning the reactivity of the N‐heterocyclic silylene Dipp2NHSi (1, 1,3‐bis(2,6‐diisopropylphenyl)‐1,3‐diaza‐2‐silacyclopent‐4‐en‐2‐ylidene) towards selected group three compounds AlI3, E(C6F5)3 (E=B, Al), elemental halides X2 (X=Br, I), tin chlorides Ph2SnCl2 and Me3SnCl, halocarbons PhCH2‐X (X=Cl, Br) and Me−I, as well as ...
Mirjam J. Krahfuss, Udo Radius
wiley +1 more source
Caracterización del sujeto Pyme [PDF]
El objetivo del trabajo es determinar la caracterización de un Constructo denominado Sujeto Pyme, a parir de un análisis multivariante. Es decir, contemplar la definición del Sujeto Pyme considerando diferentes constructos que la componen con sus ...
Muñoz, Julio César
core
Medición del clima organizacional en una Pyme del sector servicios de la región centro de Hidalgo
En los últimos años, se han incrementado las Pymes, principalmente las del sector servicios, las cuales ofrecen innumerables oportunidades para estimular el crecimiento y el empleo en un país. Sin embargo, pese a que las Pymes son el pilar fundamental de
Jocelyn Estrella Rodríguez Martínez +3 more
doaj +1 more source

