Results 51 to 60 of about 17,719 (256)

Significant kidney impairment in pediatric inflammatory bowel disease and practice points for pediatric gastroenterologists

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Children with inflammatory bowel disease (IBD) have an increased risk of developing kidney disorders, which may cause significant kidney function impairment (SKI) or lead to chronic kidney disease (CKD). In this study we aimed to provide insights in causes and diagnoses of SKI cases and to provide recommendations for pediatric ...
Stephanie A. Vuijk, Renz C. W. Klomberg, Tobias Schwerd, Anne M. Griffiths, Séamus Hussey, Matthew W. Carroll, Petter Malmborg, Protima Deb, Margreet Wessels, Natalia Mouratidou, Stephanie van Biervliet, Michael Friedt, Susie Minson, Femke H. M. Vrieling‐Prince, Nicholas M. Croft, Lissy de Ridder, the PIBD‐SETQuality Safety Registry collaborative group   +16 more
wiley   +1 more source

Pyoderma Gangrenosum After Insertion of a Hemodialysis Catheter: Koebner Phenomenon, Systemic Inflammatory Response Syndrome, and a Delay in Diagnosis

Canadian Journal of Kidney Health and Disease, 2022
Rationale: Pyoderma gangrenosum is a rare neutrophilic dermatosis. Misdiagnosis of pyoderma gangrenosum as an infection is not uncommon. Pyoderma gangrenosum can be associated with Koebner phenomenon and rarely results in systemic inflammatory response ...
Majed M. Alosaimi, Fatemah Sebzali, Ali Iqbal, Christian G. Rabbat, Catherine M. Clase   +4 more
doaj   +1 more source

Gene therapy for pyoderma gangrenosum: optimal transfection conditions and effect of drugs on gene delivery in the HaCaT cell line using cationic liposomes [PDF]

, 2016
Background/Aims: Pyoderma gangrenosum (PG) is a rare ulcerative skin disease, currently treated empirically with immunosuppression. PG is a good target for gene therapy since the skin is easily accessible.
Birchall, James Caradoc, Hargest, Rachel, Teagle, Alexandra R.   +2 more
core   +2 more sources

Safety and efficacy of weekly adalimumab 80 mg therapy in pediatric Crohn's disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Adalimumab is commonly used to induce and maintain remission in pediatric Crohn's disease (CD). However, data on the efficacy and safety of high‐dose adalimumab in this population are limited. This study aimed to evaluate the therapeutic effectiveness and safety of weekly high‐dose adalimumab (80 mg) in pediatric CD patients ...
Eyal Cohen‐Sela, Anat Yerushalmy‐Feler, Firas Rinawi, Esther Orlanski‐Meyer, Raouf Nassar, Ramit Magen‐Rimon, Yael Weintraub, Raanan Shamir, Dror S. Shouval, Manar Matar   +9 more
wiley   +1 more source

Antineutrophil cytoplasmic antibody (ANCA) in pyoderma gangrenosum, a serologic marker for associated systemic diseases: a study of eight cases [PDF]

, 2004
BACKGROUND: The pathogenesis of Ulcerative Colitis (UC) and its extraintestinal manifestations remain uncertain, although involvement of the immune system is emphasized.
Cabral, Virgínia Lúcia Ribeiro, Catapani, Wilson Roberto, Miszputen, Sender Jankiel   +2 more
core   +5 more sources

Leukocytoclastic vasculitis and necrobiotic pulmonary nodules in endoscopic remission of ulcerative colitis

JPGN Reports, EarlyView.
Abstract Skin and lung findings, including the rare findings of leukocytoclastic vasculitis (LCV) and necrobiotic pulmonary nodules, are known extraintestinal manifestations (EIMs) of inflammatory bowel disease. However, these rare EIMs have typically been reported as being a sign of active intestinal disease.
Joshua D. Noe, James Bistolarides, Karolyn A. Wanat, Yvonne Chiu   +3 more
wiley   +1 more source

A case of pyoderma gangrenosum in a dog successfully treated with prednisolone alone [PDF]

, 2015
In this case report, a markedly painful ulcerative dermatitis consistent with pyoderma granulosum is reported in a 2.5-year-old entire female Maltese dog.
Declercq, Jan
core   +1 more source

Postoperative Pyoderma Gangrenosum in Association with Renal Cell Carcinoma and Chronic Lymphocytic Leukemia [PDF]

, 2013
INTRODUCTION: Pyoderma gangrenosum (PG) is a rare sterile neutrophilic dermatosis characterized by painful recurrent ulcerations. It is frequently associated with inflammatory bowel disease, rheumatoid arthritis, or malignancies.
Caius Solovan, Claudia Wickenhauser, Elena Chiticariu, Robert Smiszek   +3 more
core   +1 more source

Surgical Reconstruction in Pyoderma Gangrenosum, a Retrospective Study of Five Patients

JEADV Clinical Practice, EarlyView.
ABSTRACT Pyoderma Gangrenosum (PG) is a neutrophilic dermatosis characterized by chronic painful ulcerations most commonly on the lower extremities. Current treatment options for PG are largely nonsurgical and include the use of systemic and topical immunomodulators and wound care.
Max E. Oscherwitz, Alysia B. Kohrs, Jacob C. Maus, Matthew L. Hrin, Maria C. Mariencheck, Joseph L. Jorizzo, Kyle E. Robinson, Joseph A. Molnar, Lindsay C. Strowd   +8 more
wiley   +1 more source

Pyoderma gangrenosum post open radical prostatectomy – A complication every urologist should consider and recognise

Urology Case Reports
Post-operative pyoderma gangrenosum is a rare neutrophilic dermatosis which forms within skin wounds following surgery. This condition is not well recognised, can be difficult to diagnose and often mimics necrotising fasciitis.
Samuel MacDiarmid, Harriet Baxter, Jordan Mann, Christophe Chemasle   +3 more
doaj   +1 more source