Results 61 to 70 of about 17,719 (256)

Health‐Related Quality of Life in Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis: A Qualitative Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Epidermal necrolysis (EN), including Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe cutaneous drug reactions with high morbidity. However, the quality of life (QoL) impact during acute hospitalization is not well understood.
Jacob McFeeters, Allison Yan, Cole Veliky, Matthew Gallardo, Kelsey Nusbaum, Rachel Kirven, Kristopher Fisher, Abraham Korman, Hyoshin Kim, Benjamin H. Kaffenberger   +9 more
wiley   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source

Expression patterns of TNFα, MAdCAM1 and STAT3 in intestinal and skin manifestations of inflammatory bowel disease [PDF]

, 2012
Background: Pathogenesis of cutaneous extraintestinal manifestations (EIM) in inflammatory bowel disease (IBD) remains elusive. Efficacy of anti-TNF agents suggests TNF-dependent mechanisms.
Biedermann, Luc, Dawson, Heather, Galván, Jose A, Greuter, Thomas, Lugli, Alessandro, Navarini, Alexander A, Prinz Vavricka, Mareike B, Rogler, Gerhard, Scharl, Michael, Schoepfer, Alain M, Soltermann, Alex, Terracciano, Luigi, Vavricka, Stephan R, Zlobec, Inti   +13 more
core   +7 more sources

Pyoderma Grangrenosum

Clinical Practice and Cases in Emergency Medicine
Case Presentation: We describe a middle-aged female with past medical history of ulcerative colitis presenting to the emergency department with bilateral painful ulcers rapidly growing on her lower legs in the prior four weeks.
Reza Aghaei, Edmund Hsu, Christopher McCoy   +2 more
doaj   +1 more source

A Case of Pyoderma Gangrenosum [PDF]

, 2012
Case Report A 60-year-old man with past medical history of hypertension, post-traumatic stress disorder, major depression, hepatic steatosis, chronic kidney disease, and untreated hepatitis C virus (genotype 1b) initially presented to the outpatient ...
Miller, MD, Christopher T.
core   +2 more sources

Characteristics and Clinical Outcomes of Patients With Hidradenitis Suppurativa (HS) Treated With Bimekizumab: A Canadian Retrospective Chart Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease characterised by painful nodules, abscesses, and draining and non‐draining tunnels. Currently, there are two biologics approved in Canada for the treatment of moderate‐to‐severe HS, adalimumab (anti‐TNF) and secukinumab (anti‐IL‐17A).
Irina Turchin, Tracey Brown‐Maher, Hélène Veillette, David O. Croitoru, Kyle Cullingham   +4 more
wiley   +1 more source

Takayasu arteritis with pyoderma gangrenosum: case reports and literature review

BMC Rheumatology, 2019
Background Takayasu arteritis is a rare, chronic inflammatory arteriopathy affecting mainly the aorta and its branches. Many skin manifestations have been reported in association with this disease.
Xuehan Zhang, Yang Jiao
doaj   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective

JEADV Clinical Practice, EarlyView.
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek, Iris Zalaudek, Karolina Zarańska, Bożena Cybulska‐Stopa   +3 more
wiley   +1 more source

Facial Pyoderma Gangrenosum – Presentation of Two Clinical Cases and Literature Review

Przegląd Dermatologiczny
Pyoderma gangrenosum is a rare neutrophilic dermatosis characterized by a distinct clinical course and typical morphology of skin lesions. Most commonly, it affects the lower legs, while head and neck involvement is extremely rare.
Małgorzata N. Grabarczyk, Kamila Zawadzińska-Halat, Jolanta Smyk, Maciej Pastuszczak   +3 more
doaj   +1 more source