Results 121 to 130 of about 412,370 (331)

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Piramida: Peninggalan Karya Seni Dunia dari Wilayah Barat Hingga Timur (Bagian I)

Humaniora, 2011
There is a terminology that human learn from the past to reach a better future. Based on this understanding, human start to learn history. Scientists learn history from historical building and cultural heritage from the past.
Hanny Wijaya
doaj  

Feature Complementarity-Guided Multi-Weight Multi-Scale Fusion Framework for Underwater Image Enhancement

Applied Sciences
The selective wavelength absorption and scattering effects caused by complex underwater optical environments lead to a significant contradiction between color restoration and structural preservation in image enhancement. To break through this bottleneck,
Gaopeixuan Sang, Tianyu Cheng, Liang Hua
doaj   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

The theory of Void in architecture

Cogent Arts & Humanities
‘Like a flood astounds an ark, so a point surmounts on the sea of perpetuity’. This paper aims to delve into the architectural narrative of space by exploring the interrelation between architectural space and the abstract concept of the Void, within a ...
Fouad Ghoussayni, Amer Ali, Ali Bayyati
doaj   +1 more source

Pyramids and cascades: a synthesis of food chain functioning and stability

, 2018
Matthieu Barbier, Michel Loreau
openalex   +2 more sources

Direct Pyramidal Tract

, 2020
National Cancer Institute
openalex   +1 more source

Until modern times there was no clear distinction between civil engineering and architecture, and the term engineer and architect were mainly geographical variations referring to the same occupation, and often used interchangeably.[9] The construction of pyramids in Egypt (c. 2700–2500 BC) were some of the first instances of large structure constructions. Other ancient historic civil engineering constructions i

, 2023
08065912405
openalex   +2 more sources

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source