Results 151 to 160 of about 5,262,176 (245)

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

SALC-Net: A lightweight contour-preserving segmentation network for yak body segmentation in complex grazing environments. [PDF]

PLoS One
Zhang W, Fu C, Xing J, Xing S, Gao D, Yao Q.   +5 more
europepmc   +1 more source

Pyramid of Secrets

It's 2554BC and Pharaoh Khafra is building a great pyramid at Giza to rival those built by his predecessors. He is also making plans for what will become one of the most famous and iconic monuments in history - the Sphinx.
Eldridge, Jim
core  

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

LapDINO: A DINOv3 and Laplacian Pyramid-Based Approach for Outdoor Terrain Segmentation. [PDF]

Sensors (Basel)
Ling S, Qin X, Xu W, Fu M, Huang H, Ma S, Liu Z.   +6 more
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Automated Renal Tumor Segmentation in Computed Tomography Images Using a Global Attention-Based DeepLabV3+ Model: Algorithm Development and Validation. [PDF]

JMIR Med Inform
Zhao Y, Liu J, Shao L, Li L, Liu Z, Liu Y, Wen J, Hao X, Li S, Zhao J, Song B.   +10 more
europepmc   +1 more source

Distant view of the Great Pyramid and the Second Pyramid [transparency] /

Title from label on top edge of lantern slide.; Part of the Australian Inland Mission collection.; Condition: Cracked.; "Trade mark ; Photos of the Gt. Pyramid ; 23" -- Printed at top of slide.; Also available in an electronic version via the Internet at:
Smyth, C. Piazzi (Charles Piazzi), 1819-1900.
core  

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

A Hybrid Multi-Scale Phase-Correlation Framework for Subpixel Registration of Multi-Temporal Very-High-Resolution Remote Sensing Images. [PDF]

J Imaging
Rasmy L, Sebari I, Ettarid M.
europepmc   +1 more source