Results 81 to 90 of about 499,076 (237)

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Micromagnetic studies of three-dimensional pyramidal shell-structures [PDF]

, 2010
In this article we present a systematic, numerical analysis of the magnetic properties of pyramidal-shaped core-shell structures in a size range below 400nm.These are three dimensional structures consisting of a ferromagnetic shell which is grown on top ...
A Knittel, Knittel, Andreas, Bending, Simon J, Bending, S., F Nasirpouri, Franchin, Matteo, Nasirpouri, F, Fangohr, Hans, Knittel, A, T Fischbacher, H Fangohr, Franchin, M, Fangohr, H, S J Bending, M Franchin, Nasirpouri, F., Fischbacher, T, Fischbacher, Thomas   +17 more
core   +2 more sources

Phenotypic Exploration in Patients with Heterozygous Variant in AFG3L2 Gene: A Case‐Series and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Variants in AFG3‐Like Matrix AAA Peptidase, Subunit 2 (AFG3L2) gene are associated with diverse clinical phenotypes. Here, we describe phenotypic findings of two unrelated children with de novo heterozygous variant and one family with inherited heterozygous variant in AFG3L2 gene.
Sangeetha Yoganathan, Laura Tochen, Jacky Ganguly, Sayoni Roy Chowdhury, Haya S AlFaris, Vivek Pai, Andrea LeBlanc‐Millar, Sara Breitbart, Hrishikesh Kumar, Manohar Shroff, Arun Reginald, Grace Yoon, Alfonso Fasano, George M Ibrahim, Carolina Gorodetsky   +14 more
wiley   +1 more source

Frequency dependence of CA3 spike phase response arising from h-current properties [PDF]

, 2013
The phase of firing of hippocampal neurons during theta oscillations encodes spatial information. Moreover, the spike phase response to synaptic inputs in individual cells depends on the expression of the hyperpolarization-activated mixed cation current (
Ole ePaulsen, Jeehyun Kwag, Melodie Borel, Hyun Jae eJang, Simone Guadagna, Borel, M, Guadagna, S, Paulsen, O, Ole Paulsen, Jang, HJ, Kwag, J, Jeehyun eKwag, Melodie eBorel, Simone eGuadagna, Hyun Jae Jang   +14 more
core   +1 more source

Diffusion Tensor Tractography of the Brainstem Pyramidal Tract: A Study on the Optimal Reduction Factor in Parallel Imaging

대한영상의학회지, 2016
Purpose Parallel imaging mitigates susceptibility artifacts that can adversely affect diffusion tensor tractography (DTT) of the pons depending on the reduction (R) factor. We aimed to find the optimal R factor for DTT of the pons that would allow us to
Yun Jung Bae, Jong Bin Park, Jae Hyoung Kim, Byung Se Choi, Cheolkyu Jung   +4 more
doaj   +1 more source

Continuous Apomorphine Infusion in Multiple System Atrophy Real‐World Insights From a French Nationwide Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Continuous subcutaneous apomorphine infusion (CSAI) is effective in Parkinson's disease but has not been evaluated in multiple system atrophy (MSA). Objective To assess the 6‐month efficacy and tolerability of CSAI in MSA patients. Methods French multicenter retrospective registry‐based analysis of CSAI use in MSA.
Simon Lamy, Frederique Leh, Alexandra Foubert‐Samier, Soizic Leguy Bonnet, Guillaume Baille, Margherita Fabbri, Margaux Dunoyer, Lise Mantisi, Caroline Giordana, Anaïs El Ouartassi, Olivier Rascol, Wassilios G. Meissner, David Bendetowicz, Marie Vanel, David Grabli, Fabienne Ory‐Magne, Sophie Drapier   +16 more
wiley   +1 more source

Projections of pyramidal tract cells to alpha‐motoneurones innervating hind‐limb muscles in the monkey

, 1975
1. We have investigated the spatial organization of monosynaptic corticospinal projections to hind‐limb motoneurones, using near threshold stimulation of the surface of the precentral gyrus to activate pyramidal tract (PT) cells and intracellular ...
Padel, Y., Tanaka, R., Jankowska, Elzbieta,   +2 more
core   +1 more source

Corticostriatal cells in comparison with pyramidal tract neurons: contrasting properties in the behaving monkey. [PDF]

, 1989
Antidromically identified neurons projecting to the putamen (CPNs) and pyramidal tract neurons (PTNs) were recorded from motor and premotor cortex of a monkey which performed a load-bearing task with the wrist.
Preuss, A., Fromm, C., Bauswein, E.
core   +1 more source

Pyramidal tract lesions and movement-associated cortical recruitment in patients with MS

, 2004
Cortical functional changes, with the potential to limit the functional consequences of tissue injury, have been shown in patients with multiple sclerosis (MS).
Falini A, Rocca MA, Gallo A, Filippi M., Colombo B, FALINI , ANDREA, COMI , GIANCARLO, FILIPPI, MASSIMO, Scotti G, Comi G, GALLO, Antonio   +10 more
core   +1 more source