Results 81 to 90 of about 888,200 (233)

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations [PDF]

open access: yes, 2004
CBS domains are defined as sequence motifs that occur in several different proteins in all kingdoms of life. Although thought to be regulatory, their exact functions have been unknown.
Anis, Miliea   +7 more
core   +6 more sources

Structural, mechanistic and regulatory studies of serine palmitoyltransferase [PDF]

open access: yes, 2012
SLs (sphingolipids) are composed of fatty acids and a polar head group derived from l-serine. SLs are essential components of all eukaryotic and many prokaryotic membranes but S1P (sphingosine 1-phosphate) is also a potent signalling molecule.
Alexeev   +56 more
core   +1 more source

Effect of an antiandrogenic H2 receptor antagonist on hepatic regeneration in rats [PDF]

open access: yes, 1988
Because biochemical 'feminization' of the liver in males is observed with hepatic regeneration and because the hepatic regenerative response in females is greater than that in males, the posibility that antiandrogens might potentiate liver regeneration ...
Chapchap, P   +7 more
core  

The Retinal TNAP [PDF]

open access: yes, 2015
Accumulating evidence from recent literature underline the important roles of tissue non specific alkaline phosphatase (TNAP) in diverse functions as well as diseases of the nervous system.
Cserpán, Dorottya   +4 more
core   +1 more source

The dabABC operon is a marker of C4-alkylated monobactam biosynthesis and responsible for (2S,3R)-diaminobutyrate production

open access: yesiScience
Summary: Non-ribosomal peptide synthetases (NRPSs) assemble metabolites of medicinal and commercial value. Both serine and threonine figure prominently in these processes and separately can be converted to the additional NRPS building blocks 2,3 ...
Rongfeng Li   +4 more
doaj   +1 more source

Extracellular ATP activates NFAT-dependent gene expression in neuronal PC12 cells via P2X receptors

open access: yesBMC Neuroscience, 2011
Background Treatment of neuronal PC12 cells with ATP induces depolarisation and increases intracellular calcium levels via purinergic receptors. In many cell types, sustained elevation of intracellular calcium levels cause changes in gene expression via ...
Becker Walter   +2 more
doaj   +1 more source

Influence of hydroxyethyl starch (6% HES 130/0.4) administration on hematology and clinical chemistry parameters [PDF]

open access: yes, 2008
Background: The chemical inertness of hydroxyethyl starch (HES) might cause interferences of the colloid with a variety of laboratory tests. We aimed to evaluate potential influences of HES 130/0.4, the newest HES type, on several common hematology and ...
Dieplinger, Benjamin   +7 more
core   +1 more source

The prevalence of the elevation serum alanine amino transaminase at gorgan in Northern Iran [PDF]

open access: yes, 2011
The elevation of serum alanine aminotranferase levels is associated most commonly with some forms of liver diseases. The aim of this study was to determine the prevalence of elevated serum alanine aminotransferase levels and the possible liver damages in
Mansourian, A.R.   +2 more
core  

Metabolic engineering of micronutrients in crop plants [PDF]

open access: yes, 2016
Micronutrient deficiency is a widespread phenomenon, most prevalent in developing countries. Being causally linked to the occurrence of a range of diseases, it affects billions of people worldwide. Enhancing the content of micronutrients in crop products
Blancquaert, Dieter   +3 more
core   +2 more sources

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