Results 301 to 310 of about 104,207 (331)
Synthetic chemistry of pyrimidines and fused pyrimidines: A review [PDF]
Synthetic Communications, 2016 AbstractReview: 100 refs.
Selvaraj Mohana Roopan, Rajesh Sompalle
openaire +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Susana Fernández +3 more
openaire +3 more sources
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Susana Fernández +3 more
openaire +3 more sources
Anticancer pyrimidines, pyrimidine nucleosides and prodrugs
1990Of the plethora of pyrimidines, pyrimidine nucleosides, analogues and prodrug derivatives that have been synthesised and evaluated as anticancer agents, only two are in general clinical use. The long-studied 5-fluorouracil (5-FUra (1), see Scheme 9.1), and some nucleoside and prodrug derivatives, are used regularly for the treatment of breast cancer ...
M. J. Robins, M. MacCoss
openaire +2 more sources
New Pyrimidine Pathway involved in the Biosynthesis of the Pyrimidine of Thiamine [PDF]
Nature, 1967 OUR, studies with mutants of Salmonella typhimurium LT2 have revealed that the pyrimidine moiety of thiamine is synthesized by a new biosynthetic route using intermediates from the purine biosynthetic pathway. Radioactive labelling has indicated that the conventional nucleic acid pyrimidine biosynthetic pathway is not used for biosynthesis of the ...
Peter C. Newell, R. G. Tucker
openaire +2 more sources
Journal of the Iranian Chemical Society, 2019
Compound 1 condensed with benzaldehyde to produce styryl pyrimidine 2. Pyridopyrimidines 5, 8 and 10 resulted from [4 + 2] cycloaddition (condensation) of 1 with malononitrile, ethyl cyanoacetate and/or ethyl acetoacetate. Compound 1 was also concerted to pyridopyrimidine 14 through multistep reaction (hydrolysis, chlorination, isothiocyanate formation
Hamed Y. Moustafa +4 more
openaire +2 more sources
Compound 1 condensed with benzaldehyde to produce styryl pyrimidine 2. Pyridopyrimidines 5, 8 and 10 resulted from [4 + 2] cycloaddition (condensation) of 1 with malononitrile, ethyl cyanoacetate and/or ethyl acetoacetate. Compound 1 was also concerted to pyridopyrimidine 14 through multistep reaction (hydrolysis, chlorination, isothiocyanate formation
Hamed Y. Moustafa +4 more
openaire +2 more sources
Receptors for Purines and Pyrimidines
Pharmacological Reviews, 1998### A. Overview Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are important signaling molecules that mediate diverse biological effects via cell-surface receptors termed purine receptors.
Vera Ralevic, Geoffrey Burnstock
openaire +3 more sources
The problem with pyrimidines [PDF]
Nature Structural & Molecular Biology, 1996 The chemical properties of cytosine present cells with a serious informational ‘disease’, necessitating enzymes with exquisite specificity for deoxyuridine for its prevention and cure.
Laurence H. Pearl, Renos Savva
openaire +1 more source
1987
Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
openaire +2 more sources
Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
openaire +2 more sources
The Effect of Different Purines and Pyrimidines on Human Pyrimidine Biosynthesis
1977Hereditary orotaciduria is caused by the patient’s inability to convert orotic acid to uridine monophosphate, due to an absence of the activity of orotidine phosphate decarboxylase in all cases and orotate phosphoribosyl-transferase in all cases but one. All or nearly all of the orotic acid formed by biosynthesis must be excreted or degraded. Therefore,
A. Rauch-Janssen +2 more
openaire +3 more sources
1975
Publisher Summary This chapter covers the literature for the period from the latter part of 1994 to the early part of 1998. This period has seen the continued use of pyrimidine drugs—such as AZT and ddC in the treatment of viral diseases and the development of new analogues of these compounds, for example, 3TC (3’-thiocytosine).
openaire +2 more sources
Publisher Summary This chapter covers the literature for the period from the latter part of 1994 to the early part of 1998. This period has seen the continued use of pyrimidine drugs—such as AZT and ddC in the treatment of viral diseases and the development of new analogues of these compounds, for example, 3TC (3’-thiocytosine).
openaire +2 more sources