Results 91 to 100 of about 3,196 (237)

Equine vegetative endocarditis and vertebral osteomyelitis due to refractory Erysipelothrix rhusiopathiae infection

Equine Veterinary Education, EarlyView.
Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou, Z. Daobry, Â. J. F. Mendes, G. Weller, S. Radhakrishnan, M. S. I. Sajib, M. Fuentes, F. Zendri, T. Forde, W. Weir, J. Del‐Pozo, D. G. M. Sutton   +11 more
wiley   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Safety and pharmacokinetics of anumigilimab for hidradenitis suppurativa or palmoplantar pustulosis: A phase 1b study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern, Simon Francis Thomsen, Georgios Kokolakis, Maurizio Podda, Gregor B. E. Jemec, Kurt Gebauer, Claus Zachariae, John Frew, Pablo Fernandez‐Peñas, Falk G. Bechara, Stefan Beissert, Sourabh Malandkar, Karen Scalzo‐Inguanti, Partha Nandy, Selvakumar Sukumar   +14 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Routine Pyrogen Testing

Journal of Pharmacy and Pharmacology, 1954
Summary The examination of preparations from large-scale manufacture for freedom from pyrogens is described. Typical results from the examination of 11. and 0·51. packs of water for injection, glucose-saline and solution and normal saline solution are presented.
openaire   +2 more sources

Development of standard consensus definitions for infectious urinary tract disease in dogs and cats, a modified Delphi study

Journal of Small Animal Practice, EarlyView.
Objectives To develop consensus‐based definitions for infectious urinary tract disease in dogs and cats. Materials and Methods A modified Delphi approach was used to develop consensus on standard terminology and definitions. Results Four rounds of review were performed with two different expert and stakeholder audiences.
J. S. Weese, F. Allerton, K. Scahill, T. M. Sørensen, L. R. Jessen   +4 more
wiley   +1 more source

Clinical benefit of faecal microbiota transplantation administered via a single retention enema as an adjunctive treatment in dogs with chronic enteropathy: a randomised controlled trial

Journal of Small Animal Practice, EarlyView.
Objectives To evaluate the clinical benefit of faecal microbiota transplantation administered via a single retention enema, as an adjunctive treatment in the management of dogs with chronic enteropathy. Materials and Methods Blinded, randomised controlled trial.
F. Allerton, M. J. Whittle, L. Durkin, C. Prior, M. Trehy, H. Swales, F. Duplan, S. Borgonovi, G. Pinchbeck, I. Gajanayake, M. Dunning, T. Sparks, P. Watson, G. C. A. Amos, K. McCallum, J. Bazelle, A. Kent   +16 more
wiley   +1 more source

Increased serum amyloid A and urinary kidney injury marker‐1 concentrations in cats with pyelonephritis: a diagnostic accuracy study

Journal of Small Animal Practice, EarlyView.
Objectives To investigate the discriminatory potential of serum amyloid A, neutrophil:lymphocyte ratio, monocyte:lymphocyte ratio and assess renal tubular injury in cats with pyelonephritis. Materials and Methods Diagnostic accuracy study using samples from prospectively enrolled cats and stored material.
L. R. Jessen, F. S. Moberg, R. Langhorn, A. S. Gravgaard, N. Dupont, N. Bak‐Jacobsen, B. J. Reezigt, A. L. Jensen, D. Bienzle, L. N. Nielsen   +9 more
wiley   +1 more source

Controlling pore size during the synthesis of hydroxyapatite nanoparticles using CTAB by the sol–gel hydrothermal method and their biological activities

Nanotechnology Reviews
Nanorod and nanosphere hydroxyapatite (HAP) particles were synthesized by the sol–gel hydrothermal method. The size of the synthesized HAP nanoparticles was controlled using cetyltrimethylammonium bromide (CTAB) as a templating agent with molar ...
Jayakodi Santhoshkumar, Shanmugam Rajeshkumar, Pandian Elumalai, Govindasamy Mani, Asiri Jaber M., Yadav Krishna Kumar, Ryeol Choi Jeong   +6 more
doaj   +1 more source

A needle in a haystack: Navigating equine injectable drug reactions

Equine Veterinary Education, EarlyView.
G. D. Hallowell
wiley   +1 more source