Results 211 to 220 of about 77,046 (386)

Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy [PDF]

open access: gold, 2018
Fan Yang   +13 more
openalex   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

Escherichia coli induces bovine neutrophil cell death independent from caspase-3/-7/-1, but with phosphatidylserine exposure prior to membrane rupture [PDF]

open access: yes, 2013
Boyen, Filip   +8 more
core   +2 more sources

Identification of pyroptosis inhibitors that target a reactive cysteine in gasdermin D [PDF]

open access: green, 2018
Jun Hu   +8 more
openalex   +1 more source

Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma

open access: yesEye &ENT Research, EarlyView.
Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen   +3 more
wiley   +1 more source

Antimicrobial Cathelicidin Peptide LL-37 Inhibits the LPS/ATP-Induced Pyroptosis of Macrophages by Dual Mechanism

open access: gold, 2014
Zhongshuang Hu   +6 more
openalex   +2 more sources

Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression [PDF]

open access: hybrid, 2018
Mi Jeong Heo   +5 more
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

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