Results 261 to 270 of about 82,547 (381)

Chemically induced dimerization of GSDMD C-terminal domain blocks GSDMD N-terminal domain-mediated pyroptosis. [PDF]

Cell Death Discov
Xu J, Fu M, Xing Y, Liang W, Li G, Zhang T, Li M, Gao C, Yang Z, Fu Y, Zhang M, Zhang Z, Zheng P, Chu X.   +13 more
europepmc   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source

Recent Insights on Inflammasomes, Gasdermin Pores, and Pyroptosis [PDF]

, 2019
Nathalia Moraes de Vasconcelos, Mohamed Lamkanfi   +1 more
openalex   +1 more source

Spermidine mitigates lipopolysaccharide-induced acute lung injury by enhancing autophagic flux. [PDF]

Biomed Rep
Zhang X, Lu H, Xu X.
europepmc   +1 more source

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

Small Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li, Qingzheng Zhang, Zongtai Liu, Weiguo Xu, Changfeng Fu, Jianxun Ding   +5 more
wiley   +1 more source

Apigenin Suppresses NLRP3 Inflammasome Activation and Pyroptosis and Promotes Functional Recovery by Promoting Mitophagy in Experimental Spinal Cord Injured Rats. [PDF]

J Inflamm Res
Wu Z, Fang Y, Dong Y, Qin Y, Liu A, Han T, Song P, Shen C.   +7 more
europepmc   +1 more source

Fine‐Tuning Photochemical Immunogenic Cell Death by a Panel of Verteporfin‐Lipid Nanoparticles: A Data‐Driven Approach

Small Science, EarlyView.
The relationship between the attributes of verteporfin‐lipid nanoparticles and the exposure of immunogenic cell death markers (HSP‐70, HMGB1, and calreticulin) following 690 nm light activation in murine pancreatic cancer cells. Immunogenic cell death (ICD) is an immunostimulatory process that can be induced by light‐activated photosensitizers, but its
Nimit Shah, Maxwell Bortei Quaye, Siddharth Reddy Soma, Meghana Sree Vadlamudi, Doha Mahmoud, Ashritha Malkoochi, Taksheel Rao Aileni, Chanda Bhandari, Kunal Karambelkar, Tayyaba Hasan, Mladen Korbelik, Baowei Fei, Xinxin Song, Girgis Obaid   +13 more
wiley   +1 more source

Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18

, 2018
Jinyong Wang, Manoranjan Sahoo, Louis Lantier, Jonathan M. Warawa, Héctor Cordero, Kelly N. Deobald, Fabio Re   +6 more
openalex   +2 more sources

Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury [PDF]

, 2019
Zhiming Ye, Li Zhang, Ruizhao Li, Wei Dong, Shuangxin Liu, Zhilian Li, Huaban Liang, Lifen Wang, Wei Shi, Asrar B. Malik, Kwong Tai Cheng, Xinling Liang   +11 more
openalex   +1 more source

Pyroptosis in Respiratory Virus Infections: A Narrative Review of Mechanisms, Pathophysiology, and Potential Therapeutic Interventions. [PDF]

Microorganisms
Lin R, Porto BN.
europepmc   +1 more source