Results 321 to 330 of about 77,046 (386)

METTL3/YTHDF3 m6A axis promotes ferroptosis in diabetic kidney disease by stabilizing TfR1

Journal of Diabetes Investigation, EarlyView.
METTL3/YTHDF3 m6A axis promoted ferroptosis in DKD by stabilizing TfR1, which could provide a reference for DKD treatment. ABSTRACT Objective Diabetic kidney disease (DKD) is a common complication of diabetes. N6‐Methyladenosine (m6A) modification is a widely studied epigenetic mechanism.
Jinmei Zhang, Xiaoping Zhou, Bin Wang, Yan Yin, Daihao Wei, Kun Li   +5 more
wiley   +1 more source

LncRNA16 inhibits pyroptosis and promotes platinum resistance in non-small cell lung cancer by sponging miRNA1827 to regulate MBD3/GSDME expression. [PDF]

Cancer Cell Int
Liu Y, Zeng Y, Wang S, Chen J, Wang Z, Zhao Y, Gong K, Wang G.   +7 more
europepmc   +1 more source

Correction to “Gut–X axis”

iMeta, EarlyView.
wiley   +1 more source

Extracellular vesicles from adipose‐derived mesenchymal stem cells prevent high glucose‐induced retinal ganglion cell pyroptosis through a microRNA‐26a‐5p‐dependent mechanism

Journal of Diabetes Investigation, EarlyView.
ADSC‐EVs carrying miR‐26a‐5p confer protection against RGC pyroptosis by targeting HDAC4 and activating H3K27ac‐dependent Nrf2 expression. ABSTRACT Objective Mesenchymal stromal/stem cells have neuroprotective effects that limit damage to the retina, which is predominantly mediated by the released extracellular vesicles (EVs).
Lei Tang, Jian Zhang, Jianping Gao
wiley   +1 more source

NAT10 inhibits the pyroptosis of laryngeal squamous cell carcinoma through ac4C modification of ELANE mRNA. [PDF]

BMC Cancer
Yu Y, Yan J.
europepmc   +1 more source

Bruxism and Stress: Ultrasonographic Masseter Muscle Assessment and Salivary Melatonin‐Cortisol Dynamics

Journal of Oral Rehabilitation, EarlyView.
ABSTRACT Background Bruxism is a parafunctional activity characterised by teeth grinding or clenching, often associated with stress and neurophysiological factors. Its aetiology is multifactorial, with recent studies emphasising neurotransmitters and hormonal imbalances, particularly melatonin and cortisol. This study assesses masseter muscle thickness
Sema Kaya, Alaettin Koç, Zübeyir Huyut
wiley   +1 more source

Nuclear Receptor ERRγ Protects Against Cardiac Ischemic Injury by Suppressing GBP5-Mediated Myocardial Inflammation. [PDF]

FASEB J
Qiu J, Che Q, Zhang Y, Chen M, Wei Z, Bai Y, Zhao T, Yan J, Wu Z, Fei Z, Wang Y, Wang Q, Li YG.   +12 more
europepmc   +1 more source

Xanthine Derivative KMUP‐3 Alleviates Periodontal Bone Resorption by Inhibiting Osteoclastogenesis and Macrophage Pyroptosis

Journal of Periodontal Research, EarlyView.
This study reveals that our self‐developed xanthine derivative, KMUP‐3, suppresses osteoclastogenesis, inflammation, and pyroptosis by inhibiting the NLRP3 inflammasome. It also alleviates periodontal bone loss in periodontitis rats, highlighting its potential as a novel therapeutic option for periodontitis.
Shang‐En Huang, Kai‐Fang Hu, Meng‐Xuan Lin, Ching‐Jiunn Tseng, Bin‐Nan Wu, Zen‐Kong Dai, Jong‐Hau Hsu, Jwu‐Lai Yeh   +7 more
wiley   +1 more source

miR-126-5p protects from URSA via inhibiting Caspase-1-dependent pyroptosis of trophoblast cells. [PDF]

Cell Mol Life Sci
Zhu X, Xu K, Ai S, Zhang Y, Chu C, Wei R, Gao S, Liu L, Li W, Zhang Y, Kikete S, Liu X, Zhang Z, Li X.   +13 more
europepmc   +1 more source