Results 341 to 350 of about 77,046 (386)

HIV-1 and SIV Infection are associated with early loss of lung interstitial CD4+ T cells and dissemination of pulmonary tuberculosis [PDF]

, 2019
et al,, Khader, Shabaana A
core   +1 more source

Vitamin D Attenuates Hepatic Sinusoidal Capillarization in Type 2 Diabetes Mellitus- Metabolic Dysfunction-Associated Fatty Liver Disease via Dual Autophagy Activation and Pyroptosis Suppression in Liver Sinusoidal Endothelial Cells. [PDF]

Biomedicines
Jiang P, Liu Y, Liu J, Quan J.
europepmc   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, EarlyView.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

Nigericin Induces Paraptosis-Like Cell Death Instead of Pyroptosis in Corneal Keratocytes. [PDF]

FASEB J
Mi X, Zhou X, Zhu S, Mateus A, Backman LJ, Danielson P.   +5 more
europepmc   +1 more source

Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

The Journal of Physiology, EarlyView.
Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai, Xijin Xu, Xia Huo, Joost H. N. Schuitemaker, Marijke M. Faas   +4 more
wiley   +1 more source

An immune activator encapsulating PD-L1 siRNA for augmented immune checkpoint blockade immunotherapy through Zn²⁺ overload triggered pyroptosis. [PDF]

J Nanobiotechnology
Gong L, Liu Y, Feng J, Xiao C, Liu C, Chen B, Chen L, Jin M, Guan Y, Gao Z, Huang W.   +10 more
europepmc   +1 more source

Gasdermin E in glioblastoma -pyroptosis resistance and tumor-promoting functions. [PDF]

Cell Death Discov
Solel E, Brudvik E, Ystaas LAR, Yabo YA, Rigg E, Choudhury RR, Saed HS, Heiland DH, Bjerkvig R, Hossain J, Miletic H.   +10 more
europepmc   +1 more source

Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict <i>Legionella</i> infection. [PDF]

mBio
Vázquez Marrero VR, Doerner J, Wodzanowski KA, Zhang J, Lu A, Boyer FD, Vargas I, Hossain S, Kammann KB, Dresler MV, Shin S.   +10 more
europepmc   +1 more source

Atractylenolide I Inhibits Nicotine-Induced Macrophage Pyroptosis and Alleviates Atherogenesis by Suppressing the TLR4/ROS/TXNIP/NLRP3 Pathway. [PDF]

Metabolites
Li HH, Liu X, Wang YP, Xu X, Zhu L, Zhang W, Ren K.   +6 more
europepmc   +1 more source

<i>Salvia miltiorrhiza</i>-derived exosome-like nanoparticles improve diabetic cardiomyopathy by inhibiting NLRP3 inflammasome-mediated macrophage pyroptosis via targeting the NEDD4/SGK1 axis. [PDF]

Nanomedicine (Lond)
Peng Z, Gong Z, Wang Z, Deng B, Zhang X, Lin J.   +5 more
europepmc   +1 more source